2-氯-1-二甲基吡嗪合成路线

参考文献

PTC THERAPEUTICS, INC.; CHEN, Guangming; DAKKA, Amal; KARP, Gary Mitchell; LI, Chunshi; NARASIMHAN, Jana; NARYSHKIN, Nikolai; WEETALL, Maria L.; WELCH, Ellen; ZHAO, Xin
Patent: WO2013/112788 A1, 2013 ;
Location in patent: Paragraph 00660 ;

1765-93-14-氟苯硼酸

38557-72-12-氯-1-二甲基吡嗪+

1092372-31-0

参考文献

Semiconductor Energy Laboratory Co., Ltd.
Patent: US2008/305361 A1, 2008 ;

60187-00-03,5-二甲基吡唑2-醇

38557-72-12-氯-1-二甲基吡嗪

参考文献

Karmas; Spoerri
Journal of the American Chemical Society, 1952 , vol. 74, p. 1580,1582

31396-38-0

38557-72-12-氯-1-二甲基吡嗪

参考文献

Dickschat, Jeroen S.; Reichenbach, Hans; Wagner-Doebler, Irene; Schulz, Stefan
European Journal of Organic Chemistry, 2005 , # 19 p. 4141 - 4153

930-61-02.4-二甲基咪唑+

67-66-3氯仿

14331-54-52,4-二甲基-嘧啶+

123-32-02,5-二甲基吡嗪+

95-89-63-氯-2,5-二甲基吡嗪+

38557-72-12-氯-1-二甲基吡嗪

参考文献

Busby, Reginald E.; Khan, Mohammad A.; Khan, Mohammad R.; Parrick, John; Shaw, C. J. Granville
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1431 - 1435

930-61-02.4-二甲基咪唑+

67-66-3氯仿

123-32-02,5-二甲基吡嗪+

95-89-63-氯-2,5-二甲基吡嗪+

38557-72-12-氯-1-二甲基吡嗪+

75712-74-24-氯-2,5-二甲基嘧啶

参考文献

Busby, Reginald E.; Khan, Mohammad A.; Khan, Mohammad R.; Parrick, John; Shaw, C. J. Granville
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1431 - 1435

930-62-12,4-二甲基咪唑+

67-66-3氯仿

4472-45-12-氨基-4-氯-6-甲基嘧啶+

95-89-63-氯-2,5-二甲基吡嗪+

38557-72-12-氯-1-二甲基吡嗪+

75712-73-1(9CI)-5-氯-2,4-二甲基嘧啶

参考文献

Busby, Reginald E.; Khan, Mohammad A.; Khan, Mohammad R.; Parrick, John; Shaw, C. J. Granville; Iqbal, Mohammad
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1427 - 1430

38557-72-12-氯-1-二甲基吡嗪

91678-81-83,5-二甲基吡嗪-2-胺

参考文献

PTC THERAPEUTICS, INC.; CHEN, Guangming; DAKKA, Amal; KARP, Gary Mitchell; LI, Chunshi; NARASIMHAN, Jana; NARYSHKIN, Nikolai; WEETALL, Maria L.; WELCH, Ellen; ZHAO, Xin
Patent: WO2013/112788 A1, 2013 ;
Location in patent: Paragraph 00661 ;

38557-72-12-氯-1-二甲基吡嗪+

74-96-4溴乙烷

13925-07-02-乙烷基-3,5-二甲基吡嗪

参考文献

Dickschat, Jeroen S.; Wickel, Susanne; Bolten, Christoph J.; Nawrath, Thorben; Schulz, Stefan; Wittmann, Christoph
European Journal of Organic Chemistry, 2010 , # 14 p. 2687 - 2695

38557-72-12-氯-1-二甲基吡嗪

60187-00-03,5-二甲基吡唑2-醇

参考文献

Ohta, Akihiro; Imazeki, Akiko; Itoigawa, Yohko; Yamada, Hiroko; Suga, Chieko; et al.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 311 - 320