您好,欢迎来到魔法化学网!
合作交流
|
服务时间(9:30-18:00)
百科
百科
▼
百科
资讯
搜索
结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
首页
化合物百科
价格行情
资讯
化工导航
实验室工具
搜索
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
2,3-二氟溴苯
合成路线
(共 5 条)
38573-88-5
2,3-二氟溴苯
→
反应条件
156682-53-0
3-溴-2-氟苯酚
+
2040-89-3
2-溴-6-氟苯酚
反应条件
1: With anhydrous potassium trimethylsilanolate in diethylene glycol dimethyl ether T=120°C; 5 h; Inert atmosphere; 2: With hydrogenchloride in diethylene glycol dimethyl ether; water T=20°C; Inert atmosphere;
参考文献
Li, Jianqing; Smith, Daniel; Qiao, Jennifer X.; Huang, Stella; Krishnananthan, Subramaniam; Wong, Henry S.; Salvati, Mark E.; Balasubramanian, Balu N.; Chen, Bang-Chi
Synlett, 2009 , # 4 p. 633 - 637
38573-88-5
2,3-二氟溴苯
+
100-51-6
苯甲醇
→
反应条件
295376-29-3
+
1036724-55-6
2-(苄氧基)-1-溴-3-氟苯
反应条件
1: benzyl alcohol With sodium hydride in tetrahydrofuran T=0°C; 0.25 h; 2: 3-bromo-1,2-difluorobenzene in tetrahydrofuran T=20°C; 17 h; Further stages. Title compound not separated from byproducts.;
参考文献
Dirr, Ronan; Anthaume, Cyril; Desaubry, Laurent
Tetrahedron Letters, 2008 , vol. 49, # 31 p. 4588 - 4590
38573-88-5
2,3-二氟溴苯
+
931-50-0
环己基溴化镁
→
反应条件
反应条件
1: 3-bromo-1,2-difluorobenzene With [PdCl2(1,3-bis(diphenylphosphino)propane)] in tetrahydrofuran Suzuki-Miyaura Coupling; 0.0833333 h; Inert atmosphereSchlenk technique; 2: cyclohexyl magnesium bromide in tetrahydrofuran T=20°C; 24 h; Inert atmosphereSchlenk technique;
参考文献
Dahadha, Adnan; Imhof, Wolfgang
Arkivoc, 2013 , vol. 2013, # 4 p. 200 - 216
38573-88-5
2,3-二氟溴苯
→
反应条件
156682-53-0
3-溴-2-氟苯酚
+
2040-89-3
2-溴-6-氟苯酚
反应条件
1: With anhydrous potassium trimethylsilanolate in diethylene glycol dimethyl ether T=120°C; 5 h; Inert atmosphere; 2: With hydrogenchloride in diethylene glycol dimethyl ether; water T=20°C; Inert atmosphere;
参考文献
Li, Jianqing; Smith, Daniel; Qiao, Jennifer X.; Huang, Stella; Krishnananthan, Subramaniam; Wong, Henry S.; Salvati, Mark E.; Balasubramanian, Balu N.; Chen, Bang-Chi
Synlett, 2009 , # 4 p. 633 - 637
38573-88-5
2,3-二氟溴苯
+
931-50-0
环己基溴化镁
→
反应条件
反应条件
1: 3-bromo-1,2-difluorobenzene With [PdCl2(1,3-bis(diphenylphosphino)propane)] in tetrahydrofuran Suzuki-Miyaura Coupling; 0.0833333 h; Inert atmosphereSchlenk technique; 2: cyclohexyl magnesium bromide in tetrahydrofuran T=20°C; 24 h; Inert atmosphereSchlenk technique;
参考文献
Dahadha, Adnan; Imhof, Wolfgang
Arkivoc, 2013 , vol. 2013, # 4 p. 200 - 216