1: With isopropylmagnesium chloride in tetrahydrofuran T=-20°C; 0.166667 h; 2: With copper(I) bromide dimethylsulfide complex in tetrahydrofuran T=-20°C; 0.00833333 h; 3: With (3,5-dinitrophenyl)(4-methylpiperazin-1-yl)methanone in tetrahydrofuran T=-20 - 20°C;

hydroxylamine hydrochloride; sodium acetate in water; acetic acid Heating;

ethyl bromide; chloro-trimethyl-silane; magnesium 1.) ether, 2.) ether, RT, 60 h; Yield given. Multistep reaction;