7-羟基-4-胆甾烯-3-酮合成路线 （共 14 条）
反应条件
1: Jone's reagent / acetone; dichloromethane / 0.5 h / 0 °C 2: potassium hydroxide; water / methanol / 16 h / 30 °C 3: perchloric acid / water / 1 h / 20 °C 4: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; trifluoroacetic acid / dimethyl sulfoxide / 40 h / 40 °C 5: water; sodium hydroxide / 0.5 h View Scheme
参考文献
Ogawa, Shoujiro; Zhou, Biao; Kimoto, Yusuke; Omura, Kaoru; Kobayashi, Akiko; Higashi, Tatsuya; Mitamura, Kuniko; Ikegawa, Shigeo; Hagey, Lee R.; Hofmann, Alan F.; Iida, Takashi
Steroids, 2013 , vol. 78, # 9 p. 927 - 937
反应条件
1: potassium hydroxide; water / methanol / 16 h / 30 °C 2: perchloric acid / water / 1 h / 20 °C 3: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; trifluoroacetic acid / dimethyl sulfoxide / 40 h / 40 °C 4: water; sodium hydroxide / 0.5 h View Scheme
参考文献
Ogawa, Shoujiro; Zhou, Biao; Kimoto, Yusuke; Omura, Kaoru; Kobayashi, Akiko; Higashi, Tatsuya; Mitamura, Kuniko; Ikegawa, Shigeo; Hagey, Lee R.; Hofmann, Alan F.; Iida, Takashi
Steroids, 2013 , vol. 78, # 9 p. 927 - 937
反应条件
1: perchloric acid / water / 1 h / 20 °C 2: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; trifluoroacetic acid / dimethyl sulfoxide / 40 h / 40 °C 3: water; sodium hydroxide / 0.5 h View Scheme
参考文献
Ogawa, Shoujiro; Zhou, Biao; Kimoto, Yusuke; Omura, Kaoru; Kobayashi, Akiko; Higashi, Tatsuya; Mitamura, Kuniko; Ikegawa, Shigeo; Hagey, Lee R.; Hofmann, Alan F.; Iida, Takashi
Steroids, 2013 , vol. 78, # 9 p. 927 - 937
反应条件
sodium acetate; chromium(II) acetate; acetic acid
参考文献
Robinson; Henderson
The Journal of organic chemistry, 1972 , vol. 37, # 4 p. 565 - 568
