2-三氟甲基-5-氯甲基吡啶合成路线 （共 3 条）
反应条件
trichlorophosphate in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
US2013/131036 A1, ;
Paragraph 1574; 1575 ;
反应条件
1: sulfuric acid / 5 h / |Reflux 2: methanol; sodium tetrahydroborate / 0 - 20 °C 3: trichlorophosphate / N,N-dimethyl-formamide / 0 - 20 °C View Scheme
反应条件
1: dimethyl sulfoxide
2: [bis(acetoxy)iodo]benzene / dichloromethane / 0 - 20 °C
3: 3-chloro-benzenecarboperoxoic acid; potassium carbonate / ethanol; water / 1.5 h / 0 - 20 °C
4: N,N,N',N',N'',N''-hexamethylphosphoric triamide; potassium hexamethylsilazane / tetrahydrofuran; toluene / -78 - 20 °C
View Scheme
参考文献
Dow AgroSciences LLC; Babcock, Jonathan M.; Young, Catherine D.; King, James E.; Kubiszak, Mary E.
Patent: US2013/288897 A1, 2013 ;
