3-三氟甲基苯基环丙基甲基酮合成路线 (共 1 条)
反应条件
1: 1-bromo-3-trifluoromethyl-benzene With n-butyllithium in hexane T=0 - 20°C; 4 h; Inert atmosphere; 2: cyclopropanecarbonitrile in hexane T=20°C; 0.166667 h; Inert atmosphere; 3: With toluene-4-sulfonic acid in hexane; water T=20°C; 0.5 h; Inert atmosphere;
参考文献
Huang, Huawen; Ji, Xiaochen; Wu, Wanqing; Jiang, Huanfeng
Chemical Communications, 2013 , vol. 49, # 32 p. 3351 - 3353