2-(3-甲氧基苯基)-5-苯基-1,3-恶唑合成路线 （共 6 条）
反应条件
pyridine; oxygen; potassium carbonate; lithium bromide; copper(ll) bromide in toluene
T=110°C; 11 h;
参考文献
Liu, Dongfang; Yu, Jintao; Cheng, Jiang
Tetrahedron, 2014 , vol. 70, # 6 p. 1149 - 1153
反应条件
tert.-butylhydroperoxide; iodine; sodium hydrogencarbonate in N,N-dimethyl-formamide
T=70°C; 10 h;
参考文献
Wan, Changfeng; Gao, Linfeng; Wang, Qiang; Zhang, Jintang; Wang, Zhiyong
Organic Letters, 2010 , vol. 12, # 17 p. 3902 - 3905
反应条件
1: 3-(methyloxy)benzaldehyde oxime With trifluorormethanesulfonic acid; silica gel in toluene
T=50°C; 0.5 h;
2: phenylacetylene in toluene
T=70°C; 3.5 h;
3: With CuCl2·2H2O; lithium chloride monohydrate; oxygen; 2,3-dicyano-5,6-dichloro-p-benzoquinone in 1,4-dioxane; propan-1-ol; toluene
T=60°C; P=9750.98 Torr; 4 h;
参考文献
Yuan, Shizhen; Li, Zhen; Xu, Ling
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 6 p. 1405 - 1409
反应条件
tert.-butylhydroperoxide; iodine in dimethyl sulfoxide
T=80°C;
参考文献
Jiang, Huanfeng; Huang, Huawen; Cao, Hua; Qi, Chaorong
Organic Letters, 2010 , vol. 12, # 23 p. 5561 - 5563
反应条件
1: toluene-4-sulfonic acid / toluene / 24 h / |Reflux
2: sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C
3: trimethylsilyl trifluoromethanesulfonate; bis-[(trifluoroacetoxy)iodo]benzene / dichloromethane; diethyl ether / -78 - 0 °C
View Scheme
参考文献
Hempel, Christian; Nachtsheim, Boris J.
Synlett, 2013 , vol. 24, # 16 art. no. ST-2013-D0547-L, p. 2119 - 2123
反应条件
1: toluene-4-sulfonic acid / toluene / 24 h / |Reflux
2: sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C
3: trimethylsilyl trifluoromethanesulfonate; bis-[(trifluoroacetoxy)iodo]benzene / dichloromethane; diethyl ether / -78 - 0 °C
View Scheme
参考文献
Hempel, Christian; Nachtsheim, Boris J.
Synlett, 2013 , vol. 24, # 16 art. no. ST-2013-D0547-L, p. 2119 - 2123
