5-(氢过氧基甲基)-1-[(2R,4S,5R)-4-羟基-5-(羟基甲基)四氢呋喃-2-基]嘧啶-2,4-二酮合成路线 （共 11 条）
反应条件
2-methyl-1,4-naphthalenedione; oxygen in water
T=4°C; 4 h; Irradiation; Further byproducts given;
参考文献
Wagner; Van Lier; Berger; Cadet
Journal of the American Chemical Society, 1994 , vol. 116, # 6 p. 2235 - 2242
反应条件
oxygen; α,α'-azodiizobutyramidine-dihydrochloride in phosphate buffer
T=40°C; pH=4.5 - 7.0; 25 h; Further byproducts given;
参考文献
Martini, Michela; Termini, John
Chemical Research in Toxicology, 1997 , vol. 10, # 2 p. 234 - 241
反应条件
dihydrogen peroxide in water
T=30°C; 15 h;
参考文献
Berger; Cadet; Ulrich
Canadian Journal of Chemistry, 1985 , vol. 63, # 1 p. 6 - 14
反应条件
1: 95 percent / TBAF*3H2O / tetrahydrofuran / 1 h / 20 °C
2: glutathione; O2 / 3 h / 37 °C
View Scheme
参考文献
In, Seok Hong; Greenberg, Marc M.
Organic Letters, 2004 , vol. 6, # 26 p. 5011 - 5013
反应条件
1: 70 percent / N-bromosuccinimide; benzoyl peroxide / CCl4 / 1 h / Heating
2: 84 percent / NaBH4 / dimethylformamide / 20 °C
3: 95 percent / TBAF*3H2O / tetrahydrofuran / 1 h / 20 °C
4: glutathione; O2 / 3 h / 37 °C
View Scheme
参考文献
In, Seok Hong; Greenberg, Marc M.
Organic Letters, 2004 , vol. 6, # 26 p. 5011 - 5013
反应条件
1: 84 percent / NaBH4 / dimethylformamide / 20 °C
2: 95 percent / TBAF*3H2O / tetrahydrofuran / 1 h / 20 °C
3: glutathione; O2 / 3 h / 37 °C
View Scheme
参考文献
In, Seok Hong; Greenberg, Marc M.
Organic Letters, 2004 , vol. 6, # 26 p. 5011 - 5013
反应条件
N-(N-L-γ-glutamyl-L-cysteinyl)glycine; oxygen
0.0833333 h; Irradiation;
参考文献
In, Seok Hong; Greenberg, Marc M.
Organic Letters, 2004 , vol. 6, # 26 p. 5011 - 5013
反应条件
1: Br2 / H2O
2: 61 percent / H2O / 2.5 h / Irradiation
3: 35 percent / H2O2 / H2O / 15 h / 30 °C
View Scheme
参考文献
Berger; Cadet; Ulrich
Canadian Journal of Chemistry, 1985 , vol. 63, # 1 p. 6 - 14
反应条件
1: 61 percent / H2O / 2.5 h / Irradiation
2: 35 percent / H2O2 / H2O / 15 h / 30 °C
View Scheme
参考文献
Berger; Cadet; Ulrich
Canadian Journal of Chemistry, 1985 , vol. 63, # 1 p. 6 - 14
反应条件
1: 64 percent / tert-butanol / H2O / 2.5 h / Irradiation
2: 39 percent / H2O2 / H2O / 15 h / 30 °C
View Scheme
参考文献
Berger; Cadet; Ulrich
Canadian Journal of Chemistry, 1985 , vol. 63, # 1 p. 6 - 14
