对苯基苯甲酰Corey醛合成路线 （共 13 条）
反应条件
N-ethyl-N,N-diisopropylamine; lithium chloride in acetonitrile
T=-15°C;
参考文献
Stjernschantz, Johan; Resul, Bahram
Patent: US2006/41016 A1, 2006 ;
Location in patent: Page/Page column 4 ;
反应条件
1: in ethylene glycol dimethyl ether; dichloromethane
T=25 - 40°C;
2: With hydrogenchloride in ethylene glycol dimethyl ether; dichloromethane; water
T=18 - 20°C;
参考文献
MATRIX LABORATORIES LTD; KARUSALA, Nageswara Rao; CHAVHAN, Bhausaheb; POTLA, Murali Krishna; JEBARAJ, Rathinapandian,; GOSULA, Veera Venkata Satya Surya Appala Narasimha Tataj; GOSULA, Shiva Kumar; BURMA, Prabhakara Rao; DATTA, Debashish
Patent: WO2010/109476 A2, 2010 ;
Location in patent: Page/Page column 13 ;
反应条件
sodium hydride
1.) DME, RT, 1 h, 2.) DME, a) 0 deg C, 30 min, b) RT, 2 h; Yield given. Multistep reaction;
参考文献
Resul, Bahram; Stjernschantz, Johan; No, Kiyo; Liljebris, Charlotta; Selen, Goeran; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 2 p. 243 - 248
