2,2-二甲基环戊烷-1,3-二酮合成路线 （共 19 条）
反应条件
copper(II) bis(trifluoromethanesulfonate); lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 30 h;
参考文献
Kobayashi, Yoshiro; Taguchi, Takeo; Morikawa, Tsutomu; Tokuno, Etsuko; Sekiguchi, Shoh
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 1 p. 262 - 267
反应条件
sodium ethanolate
1.) ethanol, RT, 15 min, 2.) reflux, 3 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Subramanyam, Ravi; Batlett, Paul D.; Iglesias, Graciela Y. Moltrasio; Watson, William H.; Galloy, Jean
Journal of Organic Chemistry, 1982 , vol. 47, # 23 p. 4491 - 4498
反应条件
boron trifluoride diethyl etherate in dichloromethane
-78 deg C -> r.t.;
参考文献
Burnell, D. Jean; Wu, Yong-Jin
Canadian Journal of Chemistry, 1990 , vol. 68, # 6 p. 804 - 811
反应条件
boron trifluoride diethyl etherate in dichloromethane
T=-78 - 20°C; Condensation;
参考文献
Reddy, Ravinder S.; Saravanan; Kumar, Pradeep
Tetrahedron, 1998 , vol. 54, # 23 p. 6553 - 6564
反应条件
1: 82 percent / KOC4H9-t / dimethylsulfoxide / 19 h / Ambient temperature
2: 82 percent / aq. HCl / 3 h / 70 °C
View Scheme
参考文献
Doyle, I. D.; Massy-Westropp, R. A.; Warren, R. F. O.
Synthesis, 1986 , # 10 p. 845 - 847
反应条件
boron trifluoride diethyl etherate; water
1.) r.t., 1 h, 2.) r.t., 1 h; Yield given. Multistep reaction;
参考文献
Jenkins; Burnell
Journal of Organic Chemistry, 1994 , vol. 59, # 6 p. 1485 - 1491
参考文献
Agosta,W.C.; Smith,A.B.
Journal of Organic Chemistry, 1970 , vol. 35, # 11 p. 3856 - 3860
反应条件
sodium hydride
1.) THF, 2.) destill., 0.013 kPa; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Garst, Michael E.; McBride, Bill J.
Journal of Organic Chemistry, 1983 , vol. 48, # 8 p. 1362 - 1364
反应条件
(i) NaOMe, MeOH, (ii) /BRN= 635994/; Multistep reaction;
参考文献
Bredereck,H. et al.
Justus Liebigs Annalen der Chemie, 1972 , vol. 762, p. 62 - 72
