乙基3-甲基-2-喹喔啉羧酸酯合成路线 （共 27 条）
反应条件
1: 83 percent / conc. HCl / 0.5 h / Ambient temperature 2: 57 percent / triethylamine / xylene / 4 h / Heating View Scheme
参考文献
Sheremet, V.I.; Dryuk, V. G.; Solomko, Z. F.; Kremlev, M. M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1981 , vol. 17, # 9 p. 941 - 945
Khimiya Geterotsiklicheskikh Soedinenii, 1981 , vol. 17, # 9 p. 1255 - 1259
反应条件
1: 83 percent / conc. HCl / 0.5 h / Ambient temperature 2: 57 percent / triethylamine / xylene / 4 h / Heating View Scheme
参考文献
Sheremet, V.I.; Dryuk, V. G.; Solomko, Z. F.; Kremlev, M. M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1981 , vol. 17, # 9 p. 941 - 945
Khimiya Geterotsiklicheskikh Soedinenii, 1981 , vol. 17, # 9 p. 1255 - 1259
反应条件
1: 24.2 g / triethylamine / ethanol / 2 h / 40 - 45 °C 2: Na2S2O4 / aq. ethanol / 3 h / Heating View Scheme
参考文献
Li, Jian-Yong; Zhang, Ji-Yu; Zhou, Xu-Zheng; Li, Jin-Shan; Lu, Run-Hua
Heterocyclic Communications, 2007 , vol. 13, # 1 p. 49 - 56
反应条件
1: 32 g / sodium hypochlorite; potassium hydroxide / aq. ethanol / 0 °C 2: 24.2 g / triethylamine / ethanol / 2 h / 40 - 45 °C 3: Na2S2O4 / aq. ethanol / 3 h / Heating View Scheme
参考文献
Li, Jian-Yong; Zhang, Ji-Yu; Zhou, Xu-Zheng; Li, Jin-Shan; Lu, Run-Hua
Heterocyclic Communications, 2007 , vol. 13, # 1 p. 49 - 56
反应条件
1: 90 percent / N-chlorosuccinimide / benzene / 2 h / Heating 2: 57 percent / triethylamine / xylene / 4 h / Heating View Scheme
参考文献
Sheremet, V.I.; Dryuk, V. G.; Solomko, Z. F.; Kremlev, M. M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1981 , vol. 17, # 9 p. 941 - 945
Khimiya Geterotsiklicheskikh Soedinenii, 1981 , vol. 17, # 9 p. 1255 - 1259
反应条件
hydrogenchloride; ethanol
参考文献
Hoffman, Robert V.; Kim, Hwa-Ok; Wilson, Anna Lee
Journal of Organic Chemistry, 1990 , vol. 55, # 9 p. 2820 - 2822
反应条件
ethanol; sodium acetate
参考文献
Wahl; Doll
Bulletin de la Societe Chimique de France, vol. 13, p. 469
反应条件
in methanol 8 h; Ambient temperature;
参考文献
Bartoszek, M.; Salzwedel, D.; Stumm, G.; Niclas, H.-J.
Organic Mass Spectrometry, 1987 , vol. 22, p. 259 - 268
反应条件
1: peroxyacetic acid 2: methanol; NH3 View Scheme
参考文献
Landquist; Silk
Journal of the Chemical Society, 1956 , p. 2052,2055
反应条件
1: With diisobutylaluminium hydride in tetrahydrofuran; toluene T=-78°C; 2: With methanol in tetrahydrofuran; toluene T=-78°C;
参考文献
MITSUBISHI TANABE PHARMA CORPORATION; MORIMOTO, Hiroshi; SAKAMOTO, Toshiaki; HIMIYAMA, Toshiyuki; KAWANISHI, Eiji; MATSUMURA, Takehiko
Patent: WO2010/30027 A1, 2010 ;
Location in patent: Page/Page column 58; 59 ;
WO 2010/030027 A1
