R(+)-alpha-甲基苄胺合成路线 (共 285 条)
反应条件
1: toluene / Heating 2: NaBH4 View Scheme
参考文献
Clayden, Jonathan; Knowles, Faye E.; Menet, Christel J.
Tetrahedron Letters, 2003 , vol. 44, # 16 p. 3397 - 3400
反应条件
1: With sodium azide; 2,4,6-triphenylpyrylium-tetrafluoroborate; triethylamine in tetrahydrofuran T=20°C; 0.333333 h; 2: With acetic acid in tetrahydrofuran T=20°C; 10 h;
参考文献
Said, Sadri A.; Fiksdahl, Anne
Tetrahedron Asymmetry, 2001 , vol. 12, # 13 p. 1947 - 1951
反应条件
1: With 2,4,6-triphenylpyrylium-tetrafluoroborate; triethylamine in tetrahydrofuran T=20°C; 0.333333 h; 2: With acetic acid in tetrahydrofuran T=20°C; 10 h;
参考文献
Said, Sadri A.; Fiksdahl, Anne
Tetrahedron Asymmetry, 2001 , vol. 12, # 13 p. 1947 - 1951
反应条件
1: With 2,4,6-triphenylpyrylium-tetrafluoroborate; triethylamine in tetrahydrofuran T=20°C; 0.333333 h; 2: With acetic acid in tetrahydrofuran T=20°C; 10 h;
参考文献
Said, Sadri A.; Fiksdahl, Anne
Tetrahedron Asymmetry, 2001 , vol. 12, # 13 p. 1947 - 1951
反应条件
schwach linksdrehendes Produkt;
参考文献
Holmberg
Chemische Berichte, 1912 , vol. 45, p. 999
反应条件
1: toluene / 14 h / 155 °C 2: NaBH4 / methanol View Scheme
参考文献
Langlois; Meyer; Soulier
Synthetic Communications, 1992 , vol. 22, # 13 p. 1895 - 1911
反应条件
1: 1,2-dichloro-ethane / 1.5 h / 30 °C 2: 9.2 g / iodine; bis(trifluoroacetoxy)iodobenzene / 1,2-dichloro-ethane 3: 96 percent / NaOH / methanol; H2O View Scheme
参考文献
JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG; ALLOLIO, Bruno; SCHIRBEL, Andreas; HAHNER, Stefanie
Patent: WO2014/48568 A1, 2014 ;
参考文献
Pettersson
Arkiv foer Kemi, 1956 , vol. 10, p. 297,299, 302
反应条件
1: T=110°C; 3 h; 2: With sodium hydroxide in water 2 h; Heating;
参考文献
Balint, Jozsef; Egri, Gabriella; Czugler, Matyas; Schindler, Jozsef; Kiss, Violetta; Juvancz, Zoltan; Fogassy, Elemer
Tetrahedron Asymmetry, 2001 , vol. 12, # 10 p. 1511 - 1518
反应条件
1: aqueous K2CO3 / toluene / 0.33 h / 0 - 10 °C 2: NaOH / toluene; H2O / 0.5 h / 40 - 45 °C View Scheme
参考文献
Zhao, Matthew M.; McNamara, James M.; Ho, Guo-Jie; Emerson, Khateeta M.; Song, Zhiguo J.; Tschaen, David M.; Brands, Karel M. J.; Dolling, Ulf-H; Grabowski, Edward J. J.; Reider, Paul J.; Cottrell, Ian F.; Ashwood, Michael S.; Bishop, Brian C.
Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6743 - 6747