R(+)-alpha-甲基苄胺合成路线 (共 285 条)
反应条件
1: With 2,4,6-triphenylpyrylium-tetrafluoroborate; triethylamine in tetrahydrofuran T=20°C; 0.333333 h; 2: With acetic acid in tetrahydrofuran T=20°C; 10 h;
参考文献
Said, Sadri A.; Fiksdahl, Anne
Tetrahedron Asymmetry, 2001 , vol. 12, # 13 p. 1947 - 1951
反应条件
1: With 2,4,6-triphenylpyrylium-tetrafluoroborate; triethylamine in tetrahydrofuran T=20°C; 0.333333 h; 2: With acetic acid in tetrahydrofuran T=20°C; 10 h;
参考文献
Said, Sadri A.; Fiksdahl, Anne
Tetrahedron Asymmetry, 2001 , vol. 12, # 13 p. 1947 - 1951
反应条件
schwach linksdrehendes Produkt;
参考文献
Holmberg
Chemische Berichte, 1912 , vol. 45, p. 999
反应条件
in ethanol; chloroform
T=30 - 55°C; 1 h; Product distribution / selectivity;
参考文献
DR. REDDY'S LABORATORIES LTD.; DR. REDDY'S LABORATORIES, INC.
Patent: WO2008/137512 A2, 2008 ;
Location in patent: Page/Page column 11 ;
反应条件
[RuCl2(IiPr)(p-cymene)]; potassium tert-butylate; tri-cyclo-hexyl-phosphine in toluene
T=110°C; 24 h; Inert atmosphere;
参考文献
Technical University of Denmark
Patent: US2011/319636 A1, 2011 ;
Location in patent: Page/Page column 9 ;
反应条件
tris(2,2,2-trifluoroethyl) borate in acetonitrile
T=80°C; 15 h;
参考文献
Lanigan, Rachel M.; Starkov, Pavel; Sheppard, Tom D.
Journal of Organic Chemistry, 2013 , vol. 78, # 9 p. 4512 - 4523
反应条件
copper diacetate in 1,1-dimethylpropan-1-ol
T=140°C; 5 h; Inert atmosphere; optical yield given as percent ee;
参考文献
Zhang, Min; Imm, Sebastian; Baehn, Sebastian; Neubert, Lorenz; Neumann, Helfried; Beller, Matthias
Angewandte Chemie - International Edition, 2012 , vol. 51, # 16 p. 3905 - 3909
参考文献
Nagao, Yoshimitsu; Yagi, Masahiro; Ikede, Takao; Fujita, Eiichi
Tetrahedron Letters, 1982 , vol. 23, # 2 p. 201 - 204
反应条件
indium tribromide
T=30 - 35°C; 0.0333333 h;
参考文献
Chakraborti, Asit K.; Chankeshwara, Sunay V.
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 14 p. 2769 - 2771
反应条件
sodium hydrogencarbonate in dichloromethane; water
T=20°C; 0.0833333 h;
参考文献
Shimizu, Mamoru; Sodeoka, Mikiko
Heterocycles, 2008 , vol. 76, # 2 p. 1301 - 1312