R(+)-alpha-甲基苄胺合成路线 (共 285 条)
反应条件
trifluoroacetic acid in methanol T=0°C; 1 h; Yield given. Title compound not separated from byproducts;
参考文献
Annunziata, Rita; Cinquini, Mauro; Cozzi, Franco
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 339 - 344
反应条件
ammonium cerium(IV) nitrate in methanol; water T=25°C; 12 h;
参考文献
Cheemala, Murthy N.; Knochel, Paul
Organic Letters, 2007 , vol. 9, # 16 p. 3089 - 3092
反应条件
1: hydrogen / (RFc)-1-Ph2P-2-((S)-MeO(2-Py)CH)ferrocene iridium complex / toluene; methanol / 2 h / 25 °C / 7500.75 Torr 2: Ce(NH4)2(NO3)6 / methanol; H2O / 12 h / 25 °C View Scheme
参考文献
Cheemala, Murthy N.; Knochel, Paul
Organic Letters, 2007 , vol. 9, # 16 p. 3089 - 3092
反应条件
menthyl (1R,2S,5R)-(-)-acetate; ethyl acetate; platinum weitgehend racemisches Praeparat ist erhalten worden;
参考文献
Allwein, Shawn P.; McWilliams, J. Christopher; Secord, Elizabeth A.; Mowrey, Dale R.; Nelson, Todd D.; Kress, Michael H.
Tetrahedron Letters, 2006 , vol. 47, # 36 p. 6409 - 6412
反应条件
1: tetrahydrofuran / 72 h / 20 °C 2: 10 percent AcOH / 1 h / 20 °C View Scheme
参考文献
Pfau, Michel; Revial, Gilbert; Guingant, Andre; d'Angelo, Jean
Journal of the American Chemical Society, 1985 , vol. 107, # 1 p. 273 - 274
反应条件
ammonia T=25°C; optical yield given as percent ee;
参考文献
Ji, Pengju; Atherton, John; Page, Michael I.
Journal of Organic Chemistry, 2011 , vol. 76, # 5 p. 1425 - 1435
反应条件
trifluoroacetic acid in methanol T=25°C; 3 h;
参考文献
Hua, Duy H.; Miao, Shou Wu; Chen, Jin Shan; Iguchi, Sadahiko
Journal of Organic Chemistry, 1991 , vol. 56, # 1 p. 4 - 6
反应条件
1: With {RuCl2(1-methyl-4-(1-methylethyl)benzene)}2; (1R,2S)-(-)-2-Amino-1,2-diphenylethanol; potassium hydroxide in isopropyl alcohol T=25°C; 24 h; 2: With hydrogenchloride in methanol optical yield given as percent eestereoselective reaction;
参考文献
Guijarro, David; Pablo, Oscar; Yus, Miguel
Tetrahedron Letters, 2009 , vol. 50, # 38 p. 5386 - 5388
反应条件
n-butyllithium in tetrahydrofuran T=0°C; 2 h; Inert atmosphere;
参考文献
Andrade, Leandro H.; Silva, Alexandre V.; Milani, Priscila; Koszelewski, Dominik; Kroutil, Wolfgang
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 9 p. 2043 - 2051
反应条件
n-butyllithium in tetrahydrofuran T=0°C; 2 h; Inert atmosphere;
参考文献
Andrade, Leandro H.; Silva, Alexandre V.; Milani, Priscila; Koszelewski, Dominik; Kroutil, Wolfgang
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 9 p. 2043 - 2051