(R)-1-(1-萘基)乙胺合成路线 （共 75 条）
反应条件
potassium carbonate in acetonitrile T=81.7°C; 5 - 22 h; Heating / reflux; Product distribution / selectivity;
参考文献
WO2006/125026 A2, ;
Page/Page column 29-31; 32; 33 ;
反应条件
1.1: sodium carbonate / N-benzyl-N,N,N-triethylammonium chloride / dichloromethane / 4 h / 25 - 40 °C 2.1: potassium carbonate / N-benzyl-N,N,N-triethylammonium chloride / isobutyl methylketone / 1 h / 20 °C 2.2: 15 h / 85 - 90 °C 3.1: potassium carbonate; thiophenol; N-benzyl-N,N,N-triethylammonium chloride / acetonitrile / 60 - 70 °C View Scheme
反应条件
potassium carbonate in dichloromethane T=38°C; 1.25 h; Product distribution / selectivity;
参考文献
WO2008/58235 A2, ;
Page/Page column 35-36 ;
反应条件
formic acid in water Formylation; Reduction; Heating;
参考文献
Meuzelaar, Gerrit J.; Karlstroem, A. Sofia E.; Klaveren, Mayra Van; Persson, Eva S. M.; Villar, Amaya Del; Koten, Gerard Van; Baeckvall, Jan-E.
Tetrahedron, 2000 , vol. 56, # 18 p. 2895 - 2903
反应条件
triethylamine in dichloromethane
T=20°C; 2 h; Inert atmosphere;
参考文献
Iwaniuk, Daniel P.; Wolf, Christian
Journal of Organic Chemistry, 2010 , vol. 75, # 19 p. 6724 - 6727
