hydrogen; palladium on activated charcoal in dichloromethane
T=20°C; 3 h;
参考文献
Kang, Ji-Hye; Peach, Megan L.; Pu, Yongmei; Lewin, Nancy E.; Nicklaus, Marc C.; Blumberg, Peter M.; Marquez, Victor E.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5738 - 5748
1: 92 percent / tetrahydrofuran / -78 - 20 °C
2: 95 percent / PCC; molecular sieves 4 Angstroem / CH2Cl2 / 24 h / 20 °C
3: 64 percent / H2 / Pd/C / CH2Cl2 / 3 h / 20 °C
View Scheme
参考文献
Kang, Ji-Hye; Peach, Megan L.; Pu, Yongmei; Lewin, Nancy E.; Nicklaus, Marc C.; Blumberg, Peter M.; Marquez, Victor E.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5738 - 5748
1: 95 percent / PCC; molecular sieves 4 Angstroem / CH2Cl2 / 24 h / 20 °C
2: 64 percent / H2 / Pd/C / CH2Cl2 / 3 h / 20 °C
View Scheme
参考文献
Kang, Ji-Hye; Peach, Megan L.; Pu, Yongmei; Lewin, Nancy E.; Nicklaus, Marc C.; Blumberg, Peter M.; Marquez, Victor E.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5738 - 5748
