2,3-二氨基-5-溴吡啶合成路线 （共 45 条）
反应条件
hydrazine hydrate; Ru-carbon in ethanol 3 h; Heating;
参考文献
Fray, M. Jonathan; Bull, David J.; Cooper, Kelvin; Parry, M. John; Stefaniak, Mark H.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 18 p. 3524 - 3535
反应条件
hydrazine in methanol; ethyl acetate
参考文献
Merck and Co., Inc.
Patent: US6025366 A1, 2000 ;
US 6025366 A
反应条件
in sodium hydroxide; ethanol
参考文献
Affinium Pharmaceuticals, Inc.
Patent: EP1226138 B1, 2004 ;
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL
Patent: US2008/125358 A1, 2008 ;
Location in patent: Page/Page column 17 ;
参考文献
Dubey, Pramod Kumar; Ratnam, C. V.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 10 p. 863 - 865
参考文献
Dubey, Pramod Kumar; Ratnam, C. V.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 10 p. 863 - 865
参考文献
Dubey, Pramod Kumar; Ratnam, C. V.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 10 p. 863 - 865
参考文献
Dubey, Pramod Kumar; Ratnam, C. V.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 10 p. 863 - 865
反应条件
sodium hydroxide; Pd/SrCO3 Hydrogenation;
参考文献
Fox; Threlfall
Org. Synth. Coll., 1973 , vol. Vol. V, p. 346
Full Text Show Details
Leese; Rydon
Journal of the Chemical Society, <1954> 4039
反应条件
orthoformic acid triethyl ester T=100°C; 3 h;
参考文献
SCHERING CORPORATION
Patent: WO2008/82487 A2, 2008 ;
Location in patent: Page/Page column 107 ;
WO 2008/082487 A2
