2,3-二氨基-5-溴吡啶合成路线

参考文献

Dubey, Pramod Kumar; Ratnam, C. V.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 10 p. 863 - 865

38875-53-52,3-二氨基-5-溴吡啶+

119-61-9二苯甲酮

65147-89-96-溴-2-苯基-1H-咪唑并[4,5-B]吡啶

参考文献

Dubey, Pramod Kumar; Ratnam, C. V.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 10 p. 863 - 865

38875-53-52,3-二氨基-5-溴吡啶+

2032-35-12-溴-1,1-二乙氧基乙烷

676371-00-96-溴-1H-咪唑并[1,2-a]吡啶-8-胺

参考文献

SCHERING CORPORATION
Patent: WO2004/26867 A2, 2004 ;
Location in patent: Page 32-33 ;
WO 2004/026867 A2

107-20-0一氯乙醛+

38875-53-52,3-二氨基-5-溴吡啶

676371-00-96-溴-1H-咪唑并[1,2-a]吡啶-8-胺

参考文献

BAYER PHARMA AKTIENGESELLSCHAFT; KOPPITZ, Marcus; KLAR, Ulrich; WENGNER, Antje; NEUHAUS, Roland; SIEMEISTER, Gerhard
Patent: WO2012/136531 A1, 2012 ;
Location in patent: Page/Page column 86 ;

38875-53-52,3-二氨基-5-溴吡啶+

17157-48-1溴乙醛

676371-00-96-溴-1H-咪唑并[1,2-a]吡啶-8-胺

参考文献

Dwyer, Michael P.; Paruch, Kamil; Alvarez, Carmen; Doll, Ronald J.; Keertikar, Kerry; Duca, Jose; Fischmann, Thierry O.; Hruza, Alan; Madison, Vincent; Lees, Emma; Parry, David; Seghezzi, Wolfgang; Sgambellone, Nicole; Shanahan, Frances; Wiswell, Derek; Guzi, Timothy J.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 22 p. 6216 - 6219

38875-53-52,3-二氨基-5-溴吡啶

128102-80-72-甲基吡啶并[2,3-b]吡嗪-3(4H)-酮

参考文献

Leese; Rydon
Journal of the Chemical Society, 1955 , p. 303,307

38875-53-52,3-二氨基-5-溴吡啶

1021919-65-26-溴-1,2-二氢-2-氧代-3H-咪唑并[4,5-b]吡啶-3-羧酸,1,1-二甲基乙酯

参考文献

UNIVERSITY OF ROCHESTER; BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA; GELBARD, Harris A.; DEWHURST, Stephen; GENDELMAN, Howard E.
Patent: WO2014/85795 A1, 2014 ;

38875-53-52,3-二氨基-5-溴吡啶

120889-04-52-羟基-1-甲基-6-苯基咪唑并[4,5-b]吡啶

参考文献

Choi, Jun Yong; Plummer, Mark S.; Starr, Jeremy; Desbonnet, Charlene R.; Soutter, Holly; Chang, Jeanne; Miller, J. Richard; Dillman, Keith; Miller, Alita A.; Roush, William R.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 2 p. 852 - 870

38875-53-52,3-二氨基-5-溴吡啶+

530-62-1N,N'-羰基二咪唑

148038-83-96-溴-1H-咪唑并[4,5-B]吡啶-2(3H)-酮

参考文献

THE REGENTS OF THE UNIVERSITY OF MICHIGAN; GLICK, Gary D.; TAYLOR, Clarke, Bentley; TOOGOOD, Peter, Laurence; VAN HUIS, Chad, Alan
Patent: WO2010/121164 A2, 2010 ;
Location in patent: Page/Page column 61 ;

38875-53-52,3-二氨基-5-溴吡啶+

57-13-6尿素

148038-83-96-溴-1H-咪唑并[4,5-B]吡啶-2(3H)-酮

参考文献

BRISTOL-MYERS SQUIBB COMPANY; JOHNSON, James A.; LLOYD, John; FINLAY, Heather; JIANG, Ji; NEELS, James; DHONDI, Naveen Kumar; GUNAGA, Prashantha; BANERJEE, Abhisek; ADISECHAN, Ashokkumar
Patent: WO2011/28741 A1, 2011 ;
Location in patent: Page/Page column 284-285 ;
WO 2011/028741 A1