(Z)-4-亚苄基-2-甲基噁唑-5(4h)-酮合成路线 （共 32 条）
反应条件
sodium hydroxide; hydrogen; sodium methylate; nickel in water 1.) 4.3 h, r.t.; 2.) 10 h, reflux; Product distribution;
参考文献
Matsue, Tomokazu; Yamada, Tsukasa; Takahashi, Hiroko; Osa, Tetsuo
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 11 p. 3690 - 3692
反应条件
hydrogenchloride; sodium hydroxide 1.) steam bath, 2.) reflux, 4 h; Multistep reaction;
参考文献
Baskar; Pandian; Priya; Chadha, Anju
Tetrahedron, 2005 , vol. 61, # 52 p. 12296 - 12306
反应条件
hydrogen; sodium methylate; nickel 1.) 10 min, 2.) 50 deg C, 2.5 h, 200 psi hydrogen; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Roper, Jerry M.; Bauer, Dennis P.
Synthesis, 1983 , # 12 p. 1041 - 1043
反应条件
1: 1.) MeONa, 2.) H2 / 2.) 10percent Pd/C / 1.) 10 min, 2.) MeOH, 50 deg C, 2-3 h 2: 93.7 percent / NaOH / H2O / Alcalase, pH 7.5 View Scheme
参考文献
Tyagi, O D; Boll, P M; Parmar, V S; Taneja, Poonam; Singh, S K
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1992 , vol. 31, # 12 p. 851 - 854
反应条件
1: 1.) sodium methoxide, 2.) H2 / 2.) Raney nickel / ethanol / 1.) 10 min, 2.) 50 deg C, 2.5 h, 200 psi hydrogen 2: 1.) hydrochloric acid, 2.) ammonia / 1.) reflux, 1.25 h, 2.) 95percent aq. ethanol, reflux View Scheme
参考文献
Roper, Jerry M.; Bauer, Dennis P.
Synthesis, 1983 , # 12 p. 1041 - 1043
反应条件
sodium acetate; acetic anhydride
0.0666667 h; microwave irradiation;
参考文献
Baskar; Pandian; Priya; Chadha, Anju
Tetrahedron, 2005 , vol. 61, # 52 p. 12296 - 12306
反应条件
sodium acetate; acetic anhydride
T=100 - 110°C; 4 h;
参考文献
Blanco-Lomas, Marina; Campos, Pedro J.; Sampedro, Diego
Organic Letters, 2012 , vol. 14, # 17 p. 4334 - 4337
参考文献
Brenner; Ruefenacht
Helvetica Chimica Acta, 1954 , vol. 37, p. 203,208
反应条件
sodium acetate
1 h; Heating;
参考文献
Roper, Jerry M.; Bauer, Dennis P.
Synthesis, 1983 , # 12 p. 1041 - 1043
反应条件
in benzene
0.166667 h; Heating;
参考文献
Kumar, Pradeep; Mishra, Harendra D.; Mukerjee, Arya K.
Synthesis, 1980 , # 10 p. 836 - 839
