Ellingboe, John W.; Lombardo, Louis J.; Alessi, Thomas R.; Nguyen, Thomas T.; Guzzo, Frieda; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 17 p. 2485 - 2493
1: 100 percent / SOCl2, DMF / CH2Cl2 / 18 h
2: 93 percent / AlCl3 / CH2Cl2 / 0.25 h / -10 °C
3: 100 percent / TiCl4 / CH2Cl2; tetrahydrofuran / 2 h / 0 °C
4: 70 percent / Ph3COH, TFA / 48 h / Ambient temperature
5: 98 percent / N-methylpyrrolidinone / 3.5 h / Heating
View Scheme
参考文献
Ellingboe, John W.; Lombardo, Louis J.; Alessi, Thomas R.; Nguyen, Thomas T.; Guzzo, Frieda; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 17 p. 2485 - 2493
1: 93 percent / AlCl3 / CH2Cl2 / 0.25 h / -10 °C
2: 100 percent / TiCl4 / CH2Cl2; tetrahydrofuran / 2 h / 0 °C
3: 70 percent / Ph3COH, TFA / 48 h / Ambient temperature
4: 98 percent / N-methylpyrrolidinone / 3.5 h / Heating
View Scheme
参考文献
Ellingboe, John W.; Lombardo, Louis J.; Alessi, Thomas R.; Nguyen, Thomas T.; Guzzo, Frieda; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 17 p. 2485 - 2493
1: 100 percent / TiCl4 / CH2Cl2; tetrahydrofuran / 2 h / 0 °C
2: 70 percent / Ph3COH, TFA / 48 h / Ambient temperature
3: 98 percent / N-methylpyrrolidinone / 3.5 h / Heating
View Scheme
参考文献
Ellingboe, John W.; Lombardo, Louis J.; Alessi, Thomas R.; Nguyen, Thomas T.; Guzzo, Frieda; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 17 p. 2485 - 2493
1: 70 percent / Ph3COH, TFA / 48 h / Ambient temperature
2: 98 percent / N-methylpyrrolidinone / 3.5 h / Heating
View Scheme
参考文献
Ellingboe, John W.; Lombardo, Louis J.; Alessi, Thomas R.; Nguyen, Thomas T.; Guzzo, Frieda; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 17 p. 2485 - 2493
