1,1-双-(4-氟苯基)-1,3-丁二烯合成路线 （共 8 条）
反应条件
1: C17H17FN2O2S With dichloro bis(acetonitrile) palladium(II); lithium tert-butylate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in 1,4-dioxane
0.0166667 h; Inert atmosphere;
2: 1-bromo-4-fluorobenzene in 1,4-dioxane
T=90°C; 2 h; Inert atmosphere;
参考文献
Yang, Qin; Chai, Huining; Liu, Tingting; Yu, Zhengkun
Tetrahedron Letters, 2013 , vol. 54, # 48 p. 6485 - 6489
反应条件
tris-(dibenzylideneacetone)dipalladium(0); lithium tert-butylate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in 1,4-dioxane
T=80°C; 12 h; Inert atmosphere;
参考文献
Zhou, Lei; Ye, Fei; Zhang, Yan; Wang, Jianbo
Organic Letters, 2012 , vol. 14, # 3 p. 922 - 925
反应条件
tris-(dibenzylideneacetone)dipalladium(0); lithium tert-butylate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in 1,4-dioxane
T=80°C; 12 h; Inert atmosphere;
参考文献
Zhou, Lei; Ye, Fei; Zhang, Yan; Wang, Jianbo
Organic Letters, 2012 , vol. 14, # 3 p. 922 - 925
反应条件
RhH(CO)(triphenylphosphine)3 in toluene
T=50°C; 24 h;
参考文献
Nishihara, Yasushi; Yoda, Chikako; Itazaki, Masumi; Osakada, Kohtaro
Bulletin of the Chemical Society of Japan, 2005 , vol. 78, # 8 p. 1469 - 1480
反应条件
1.1: ethanol / |Reflux; |Inert atmosphere
2.1: dichloro bis(acetonitrile) palladium(II); 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; lithium tert-butylate / 1,4-dioxane / 0.02 h / |Inert atmosphere
2.2: 2 h / 90 °C / |Inert atmosphere
View Scheme
参考文献
Yang, Qin; Chai, Huining; Liu, Tingting; Yu, Zhengkun
Tetrahedron Letters, 2013 , vol. 54, # 48 p. 6485 - 6489
反应条件
1: aq. HCl, AcOH
2: (i) MeI, (ii) aq. NaOH
View Scheme
参考文献
Holm,T.
Acta Chemica Scandinavica (1947-1973), 1963 , vol. 17, p. 2437 - 2443
反应条件
1: (i) Mg, EtBr, (ii) /BRN= 516231/
2: aq. HCl, AcOH
3: (i) MeI, (ii) aq. NaOH
View Scheme
参考文献
Holm,T.
Acta Chemica Scandinavica (1947-1973), 1963 , vol. 17, p. 2437 - 2443
反应条件
(i) MeI, (ii) aq. NaOH; Multistep reaction;
参考文献
Holm,T.
Acta Chemica Scandinavica (1947-1973), 1963 , vol. 17, p. 2437 - 2443
