1-Β-D-呋喃核糖基-1H-1,2,4-三氮唑-3-羧酸甲酯合成路线 (共 3 条)
反应条件
ammonia in methanol T=20°C; 4 h;
参考文献
Clariant Life Science Molecules (Italia) SpA
Patent: EP1281715 B1, 2003 ;
Location in patent: Page/Page column 6 ;
反应条件
sodium methylate in methanol
T=20°C; 2 h;
参考文献
Kumarapperuma, Sidath C.; Sun, Yanjie; Jeselnik, Marjan; Chung, Kiwon; Parker, William B.; Jonsson, Colleen B.; Arterburn, Jeffrey B.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 11 p. 3203 - 3207
反应条件
perchloric acid in acetone
T=0 - 20°C;
参考文献
Wang, Guangyi; Sakthivel, Kandasamy; Rajappan, Vasanthakumar; Bruice, Thomas W.; Tucker, Kathleen; Fagan, Patrick; Brooks, Jennifer L.; Hurd, Tiffany; Leeds, Janet M.; Cook, P. Dan
Nucleosides, Nucleotides and Nucleic Acids, 2004 , vol. 23, # 1-2 p. 317 - 337