4-(叔丁基)-2-碘苯酚合成路线 （共 5 条）
反应条件
copper(l) iodide; 1,10-phenanthroline; caesium carbonate in 1,4-dioxane T=90°C; 24 h; Inert atmosphere;
参考文献
Chen, Dingben; Shen, Guodong; Bao, Weiliang
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 19 p. 4067 - 4073
反应条件
hydrogenchloride; α,α,α-trifluorotoluene; dihydrogen peroxide; iodine in 2,2,2-trifluoroethanol; water
T=20°C; 4 h;
参考文献
Bedrac, Leon; Iskra, Jernej
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 7 p. 1243 - 1248
反应条件
chloramine-T; sodium iodide in N,N-dimethyl-formamide
T=20°C;
参考文献
Pan, Wen-Bin; Chen, Chin-Chau; Wei, Li-Lan; Wei, Li-Mei; Wu, Ming-Jung
Tetrahedron Letters, 2013 , vol. 54, # 21 p. 2655 - 2657
反应条件
sulfuric acid; acetic acid
6 h; Ambient temperature;
参考文献
Siu, Anna F. M.; Lambrecht, Richard M.; Shani, Jashovam; Pyne, Stephen G.; Kane-Maguire, Leon A. P.
Journal of Labelled Compounds and Radiopharmaceuticals, 1997 , vol. 39, # 9 p. 711 - 729
反应条件
1: conc. H2SO4, HOAc / 16 h / 22 °C
2: conc. HCl / ethanol / 1.5 h / Heating
View Scheme
参考文献
Stokker; Deana; deSolms; Schultz; Smith; Cragoe Jr.; Baer; Ludden; Russo; Scriabine; Sweet; Watson
Journal of Medicinal Chemistry, 1980 , vol. 23, # 12 p. 1414 - 1427
