3-(4-氟苯基)-3-(4-甲基苯基)丙酸合成路线 （共 5 条）
反应条件
Pd-BaSO4; ethanol
Hydrogenation;
参考文献
Bergmann et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 1612,1614
反应条件
sulfuric acid; acetic acid
24 h; Heating; Yield given;
参考文献
Bogeso
Journal of Medicinal Chemistry, 1983 , vol. 26, # 7 p. 935 - 947
反应条件
1: 1.) Mg / 1.) ether, 2.) ether, toluene, reflux, 30 min
2: aq. H2SO4, CH3COOH / 24 h / Heating
View Scheme
参考文献
Bogeso
Journal of Medicinal Chemistry, 1983 , vol. 26, # 7 p. 935 - 947
反应条件
1: 1.) Mg / 1.) ether, 2.) ether, toluene, reflux, 30 min
2: aq. H2SO4, CH3COOH / 24 h / Heating
View Scheme
参考文献
Bogeso
Journal of Medicinal Chemistry, 1983 , vol. 26, # 7 p. 935 - 947
反应条件
PPA; Polyphosphoric acid (PPA)
T=95°C; 3 h;
参考文献
Bogeso
Journal of Medicinal Chemistry, 1983 , vol. 26, # 7 p. 935 - 947
