6-甲氧基-2-乙酰萘合成路线 （共 124 条）
反应条件
1: 1-(6-methoxy-2-naphthyl)-1-ethanone With hydrogenchloride; triethylamine in dichloromethane; water T=85°C; 2: dimethylammonium chloride With Na2S2O5; sodium hydroxide in water T=140°C; 48 h; Autoclave;
参考文献
Yao, Wei; Yan, Yongli; Xue, Lin; Zhang, Chuang; Li, Guoping; Zheng, Qingdong; Zhao, Yong Sheng; Jiang, Hua; Yao, Jiannian
Angewandte Chemie - International Edition, 2013 , vol. 52, # 33 p. 8713 - 8717
Angew. Chem., 2013 , vol. 125, # 33 p. 8875 - 8879,5
反应条件
1: acetic acid; hydrogen bromide / water / 12 h / 100 °C 2: Na2S2O5; ammonium hydroxide / water / 96 h / 100 °C 3: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 9 - 13 h / 75 °C View Scheme
参考文献
Shin, Sung Min; Lee, Mi Sun; Han, Ji Hee; Jeong, Nakcheol
Chemical Communications, 2014 , vol. 50, # 3 p. 289 - 291
反应条件
1.1: potassium sec-butoxide / dimethyl sulfoxide / 1 h / 50 - 60 °C 1.2: pH 2 2.1: hydrogen; palladium 10 on activated carbon; sulfuric acid / ethyl acetate 3.1: sulfuric acid View Scheme
参考文献
Prabhakar; Reddy, C. Bakki; Reddy, Ch. Maheedhara; Nageshwar; Devi, A. Sivalakshmi; Babu, J. Moses; Vyas; Sarma; Reddy
Organic Process Research and Development, 1999 , vol. 3, # 2 p. 121 - 125
反应条件
1: POCl3 / 20 °C 2: NaOH / dioxane; H2O / 20 °C View Scheme
参考文献
Kotha; Tafesh; Davenport; Ortiz
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001 , vol. 40, # 12 p. 1166 - 1169
反应条件
1: tetramethylammonium hydroxide / methanol / 0 - 20 °C 2: p-toluenesulfonic acid / benzene / 4 h / Heating View Scheme
参考文献
Kameo; Asami; Ogawa; Matsunaga; Saito; Tomisawa; Sota
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 5 p. 1260 - 1267
参考文献
Thomae GmbH
Patent: DE2047806 , 1972 ;
Chem.Abstr., 1972 , vol. 77, # 19386
反应条件
hydrogenchloride in dichloromethane 2 h; Heating;
参考文献
Barrio, Jorge R.; Petric, Andre J.; Satyamurthy, Nagichettiar; Kepe, Vladimir; Small, Gary W.
Patent: US2007/53831 A1, 2007 ;
Location in patent: Page/Page column 7 ;
反应条件
copper(I) bromide in ethanol T=60°C; Inert atmosphere;
参考文献
Su, Qiong; Zhao, Zi-Jian; Xu, Feng; Lou, Peng-Cai; Zhang, Kai; Xie, De-Xun; Shi, Lei; Cai, Qing-Yun; Peng, Zhi-Hong; An, De-Lie
European Journal of Organic Chemistry, 2013 , # 8 p. 1551 - 1557
反应条件
2-carboxyethyl triphenyl phosphonium tribromide in tetrahydrofuran T=25°C; 6 h;
参考文献
Phosphorus and Sulfur and the Related Elements, , vol. 25, p. 357 - 368
反应条件
hydrogenchloride; hydrogen sulfide; sodium carbonate; acetic acid in water
参考文献
American Home Products Corporation
Patent: US5084575 A1, 1992 ;
