6-甲氧基-2-乙酰萘合成路线 （共 124 条）
反应条件
morpholine; sulfur T=140°C; Erhitzen des Reaktionsgemisches mit Essigsaeure und wss. Salzsaeure;
参考文献
Mueller; Seres; Steiner; et al.
Helvetica Chimica Acta, 1974 , vol. 57, # 3 p. 790 - 795
反应条件
hydrogen; palladium on activated charcoal; 5 percent palladium-carbon in tetrahydrofuran
参考文献
Xie, Bao-Han; Xia, Chun-Gu; Lu, Shi-Jie; Chen, Ke-Jun; Kou, Yuan; Yuan-Qi, Yin
Tetrahedron Letters, 1998 , vol. 39, # 40 p. 7365 - 7368
反应条件
samarium in methanol T=20°C; reductive coupling; 20 h;
参考文献
Tetrahedron Letters, , vol. 41, # 20 p. 3793 - 3796
反应条件
1: t-BuOK / hexane / 0.5 h / 20 °C 2: H2, HClO4 / 10 percent Pd/C / hexane / 20 °C View Scheme
参考文献
Hurusawa, Shinya; Nakamura, Shuji; Yagi, Sayoko; Kurihara, Takushi; Hamada, Yasumasa; Shioiri, Takayuki
Synthetic Communications, 1984 , vol. 14, # 14 p. 1365 - 1372
反应条件
lithium aluminium tetrahydride; titanium tetrachloride in tetrahydrofuran T=-5°C; 0.5 h;
参考文献
Garcia, Mariano; Del Campo, Carmen; Sinisterra, Jose V.; Llama, Emilio F.
Tetrahedron Letters, 1993 , vol. 34, # 49 p. 7973 - 7974
反应条件
pyridine; water; iodine in methanol T=30°C; other temperatures; ΔH(excit.); KineticsMechanismThermodynamic data;
参考文献
Ananthakrishnanadar, P.; Gnanasekaran, C.
Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical & Analytical, 1980 , vol. 19, # 7 p. 646 - 649
反应条件
1: 90 percent / diethyl ether / 1.) 20 deg C, 10 h, 2.) reflux, 30 min 2: 90 percent / POCl3, Py / CH2Cl2 / 0 - 25 °C View Scheme
参考文献
Fouquey; Jacques; Azadian-Boulanger
European Journal of Medicinal Chemistry, 1978 , vol. 13, # 4 p. 303 - 308
反应条件
1: HN3, H2SO4 / CHCl3 2: aq. H2SO4 / ethanol View Scheme
参考文献
Abbott Laboratories
Patent: US5681842 A1, 1997 ;
反应条件
morpholine; hydrogenchloride; acetic acid 1.) reflux, 18 h, 2.) reflux, 24 h; Yield given. Multistep reaction;
参考文献
Synthetic Communications, , vol. 21, # 12-13 p. 1353 - 1360
反应条件
hydrazine hydrate; diethylene glycol T=120°C; Versetzen mit KOH und Kochen des Reaktionsgemisches unter Abdestillieren des entstehenden Wassers;
参考文献
Cagniant,P. et al.
Bulletin de la Societe Chimique de France, 1961 , p. 1938 - 1941
