1,4-二甲氧基-2,3-甲基苯合成路线 （共 18 条）
参考文献
Rinke; Gruenert; Bednarski
Pharmazie, 2001 , vol. 56, # 10 p. 763 - 769
参考文献
Rathore; Bosch; Kochi
Tetrahedron, 1994 , vol. 50, # 23 p. 6727 - 6758
反应条件
1: N-bromosuccinimide / peroxyde de benzoyle / CCl4 / Heating
2: d'iodure de sodium / dimethylformamide / 90 °C
3: 41 percent / d'iodure de sodium / dimethylformamide / 24 h / 90 °C
View Scheme
参考文献
Laduranty, Joelle; Lepage, Lucette; Lepage, Yves
Canadian Journal of Chemistry, 1980 , vol. 58, p. 1161 - 1167
反应条件
1: N-bromosuccinimide / peroxyde de benzoyle / CCl4 / Heating
2: d'iodure de sodium / dimethylformamide / 90 °C
3: 37 percent / d'iodure de sodium / dimethylformamide / 24 h / 90 °C
View Scheme
参考文献
Laduranty, Joelle; Lepage, Lucette; Lepage, Yves
Canadian Journal of Chemistry, 1980 , vol. 58, p. 1161 - 1167
反应条件
1: N-bromosuccinimide / peroxyde de benzoyle / CCl4 / Heating
2: d'iodure de sodium / dimethylformamide / 90 °C
3: 41 percent / d'iodure de sodium / dimethylformamide / 24 h / 90 °C
4: 58 percent / nitrate d'ammonium et de cerium / acetonitrile; acetone
View Scheme
参考文献
Laduranty, Joelle; Lepage, Lucette; Lepage, Yves
Canadian Journal of Chemistry, 1980 , vol. 58, p. 1161 - 1167
反应条件
aluminium trichloride in nitromethane
T=80°C; 5 h;
参考文献
Sartori, Giovanni; Bigi, Franca; Goffredi, Gino; Maggi, Raimondo; Portioli, Roberto; Casnati, Giuseppe
Journal of Chemical Research, Miniprint, 1993 , # 8 p. 2061 - 2079
反应条件
1: aq. HCl
2: AcOH
3: aq. KOH, EtOH
View Scheme
参考文献
Lin; Cosby; Shansky; Sartorelli
Journal of medicinal chemistry, 1972 , vol. 15, # 12 p. 1247 - 1252
反应条件
cerium ammonium nitrate; silica gel in dichloromethane
0.25 h;
参考文献
Ali, Mohammed Hashmat; Niedbalski, Melinda; Bohnert, Gary; Bryant, Daniel
Synthetic Communications, 2006 , vol. 36, # 12 p. 1751 - 1759
