1: para-bromotoluene With iodine; magnesium in diethyl ether
Inert atmosphere;
2: crotonic acid in diethyl ether
Inert atmosphereReflux; Further stages;
参考文献
Deasy, Rebecca E.; Brossat, Maude; Moody, Thomas S.; Maguire, Anita R.
Tetrahedron Asymmetry, 2011 , vol. 22, # 1 p. 47 - 61