5-氯苯并呋咱 3-氧化物合成路线 （共 12 条）
反应条件
potassium hydroxide; sodium hypochlorite in ethanol T=0 - 20°C;
参考文献
Carta, Antonio; Paglietti, Giuseppe; Rahbar Nikookar, Mohammad E; Sanna, Paolo; Sechi, Leonardo; Zanetti, Stefania
European Journal of Medicinal Chemistry, 2002 , vol. 37, # 5 p. 355 - 366
反应条件
sodium azide; benzyl-tri-(n-butyl)-ammonium bromide in 1,2-dichloro-ethane T=60°C; 6 h;
参考文献
Ayyangar, N. R.; Madan Kumar, S.; Srinivasan, K. V.
Synthesis, 1987 , # 7 p. 616 - 618
反应条件
in acetic acid T=110°C; 6 h;
参考文献
Leyva, Elisa; Leyva, Socorro; Gonzalez-Balderas, Regina M.; De Loera, Denisse; Jimenez-Catano, Rogelio
Mendeleev Communications, 2013 , vol. 23, # 4 p. 217 - 218
反应条件
diethyl 2-oxosuccinate sodium salt in ethanol T=55°C; 4 h; Further byproducts given;
参考文献
Bertelli, Lucia; Biagi, Giuliana; Giorgi, Irene; Manera, Clementina; Livi, Oreste; Scartoni, Valerio; Betti, Laura; Giannaccini, Gino; Trincavelli, Letizia; Barili, Pier Luigi
European Journal of Medicinal Chemistry, 1998 , vol. 33, # 2 p. 113 - 122
反应条件
in ethanol T=55°C; 4 h; Further byproducts given;
参考文献
Bertelli, Lucia; Biagi, Giuliana; Giorgi, Irene; Manera, Clementina; Livi, Oreste; Scartoni, Valerio; Betti, Laura; Giannaccini, Gino; Trincavelli, Letizia; Barili, Pier Luigi
European Journal of Medicinal Chemistry, 1998 , vol. 33, # 2 p. 113 - 122
反应条件
acetonedicarboxylic acid diethyl ester; sodium ethanolate in ethanol 5 h; Ambient temperature;
参考文献
Bertelli, Lucia; Biagi, Giuliana; Giorgi, Irene; Livi, Oreste; Manera, Clementina; Scartoni, Valerio; Martini, Claudia; Giannaccini, Gino; Trincavelli, Letizia; Barili, Pier Luigi
Farmaco, 1998 , vol. 53, # 4 p. 305 - 311
反应条件
sodium ethanolate in ethanol 5 h; Ambient temperature;
参考文献
Bertelli, Lucia; Biagi, Giuliana; Giorgi, Irene; Livi, Oreste; Manera, Clementina; Scartoni, Valerio; Martini, Claudia; Giannaccini, Gino; Trincavelli, Letizia; Barili, Pier Luigi
Farmaco, 1998 , vol. 53, # 4 p. 305 - 311
反应条件
potassium hydroxide; hydroxylamine in ethanol T=20°C; 1 h;
参考文献
Crampton, Michael R.; Lunn, Rachel E.A.; Lucas, David
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 19 p. 3438 - 3443
反应条件
pyrrolidine; triethylamine T=0 - 20°C;
参考文献
Torres, Enrique; Moreno, Elsa; Ancizu, Saioa; Barea, Carlos; Galiano, Silvia; Aldana, Ignacio; Monge, Antonio; Perez-Silanes, Silvia
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 12 p. 3699 - 3703
反应条件
tin(ll) chloride in ethanol; water 1 h; Reflux;
参考文献
Shi, Da-Qing; Dou, Guo-Lan; Ni, Sai-Nan; Shi, Jing-Wen; Li, Xiao-Yue
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 6 p. 1797 - 1801
