N-(4-甲氧基苄基)-1-丁胺合成路线 （共 8 条）
反应条件
1: (4-methoxyphenyl)methanol With titanium tetrachloride in chloroform T=20°C; 0.0166667 h; Molecular sieve; 2: N-butylamine in chloroform 36 h; Reflux;
参考文献
Tsai, Chen-Yu; Sung, Robert; Zhuang, Bo-Ren; Sung, Kuangsen
Tetrahedron, 2010 , vol. 66, # 34 p. 6869 - 6872
反应条件
sodium tetrahydroborate; nickel dichloride in methanol T=20°C; Reductive amination; 0.166667 h;
参考文献
Saxena, Ira; Borah, Ruli; Sarma, Jadab C.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 4 p. 503 - 504
反应条件
sodium tetrahydroborate; iodine in methanol T=20°C; 0.166667 h;
参考文献
Saxena, Ira; Borah, Ruli; Sarma, Jadab C.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 9 p. 1970 - 1971
反应条件
aluminium; mercury dichloride in ethanol T=100°C; 4 h;
参考文献
Angerer, Erwin von; Egginger, Guenter; Kranzfelder, Gerhard; Bernhauer, Horst; Schoenenberger, Helmut
Journal of Medicinal Chemistry, 1982 , vol. 25, # 7 p. 832 - 837
反应条件
1: CHCl3 / 1 h / Ambient temperature 2: Al, HgCl2 / ethanol / 4 h / 100 °C View Scheme
参考文献
McSkimming, Alex; Bhadbhade, Mohan M.; Colbran, Stephen B.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 12 p. 3411 - 3416
Angew. Chem., 2013 , vol. 125, # 12 p. 3495 - 3500,6
反应条件
formic acid; C34H39ClN3O4Rh(2+)*2F6P(1-); sodium formate; silver trifluoromethanesulfonate in methanol; water T=21.84°C; 16 h; Schlenk techniqueInert atmosphere; Reagent/catalyst;
参考文献
McSkimming, Alex; Bhadbhade, Mohan M.; Colbran, Stephen B.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 12 p. 3411 - 3416
Angew. Chem., 2013 , vol. 125, # 12 p. 3495 - 3500,6
反应条件
sodium tetrahydroborate; tin(IV) chloride 1.) CH2Cl2, 2.) MeOH; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Pearson, William H.; Fang, Wen-kui
Journal of Organic Chemistry, 1995 , vol. 60, # 16 p. 4960 - 4961
反应条件
in nitrobenzene T=40°C; ΔH(activ.), ΔS(activ.); Rate constantThermodynamic dataMechanism;
参考文献
Shpan'ko, I. V.; Korostylev, A. P.; Rusu, L. N.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, p. 1715 - 1723
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 9 p. 1881 - 1888
