3-氯-1-茚满-5-基-丙-1-酮合成路线 （共 2 条）
反应条件
AlCl3, aluminium chloride in dichloromethane T=0 - 20°C; Friedel-Crafts acylation; Inert atmosphere;
参考文献
Ivchenko; Nifant'Ev; Ustynyuk; Ezerskii
Russian Chemical Bulletin, 2009 , vol. 58, # 5 p. 929 - 935
反应条件
1.1: H2SO4 / 48 h / 55 - 60 °C
2.1: HNO3; H2SO4 / 2 h / 0 - 5 °C
2.2: 8.8 kg / methanesulfonic acid; H2 / palladium hydroxide on carbon / methanol; H2O / 9 h / 2585.74 Torr
View Scheme
参考文献
Urban, Frank J.; Jasys, V. John; Raggon, Jeffrey W.; Buzon, Richard A.; Hill, Paul D.; Eggler, James F.; Weaver, John D.
Synthetic Communications, 2003 , vol. 33, # 12 p. 2029 - 2043
