4-氨基四氢噻喃-4-甲酸合成路线 （共 3 条）
反应条件
hydrogenchloride; water
Heating / reflux;
参考文献
MITSUBISHI TANABE PHARMA CORPORATION
Patent: WO2008/4698 A2, 2008 ;
Location in patent: Page/Page column 125 ;
反应条件
barium dihydroxide; water in ethanol
T=100°C; 24 h;
参考文献
Lavrador, Karine; Guillerm, Danielle; Guillerm, Georges
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 13 p. 1629 - 1634
反应条件
1: methanol; H2O / 50 °C
2: Ba(OH)2, H2O / ethanol / 24 h / 100 °C
View Scheme
参考文献
Lavrador, Karine; Guillerm, Danielle; Guillerm, Georges
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 13 p. 1629 - 1634
