4-(苯基甲基)-(9ci)-1-哌嗪胺合成路线 （共 4 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 3 h; Reflux;
参考文献
Zhang, Yinsheng; Stolle, Wayne T.
Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 5-6 p. 487 - 489
反应条件
1: Et3N / acetonitrile / 3 h / Heating 2: 33 percent / Zn; aq. HCl / methanol / 2 h / Heating View Scheme
参考文献
Zhang, Yinsheng; Stolle, Wayne T.
Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 5-6 p. 487 - 489
反应条件
1: NaNO2; aqueous HCl 2: zinc-powder; aqueous acetic acid View Scheme
参考文献
KARYOPHARM THERAPEUTICS, INC.; SANDANAYAKA, Vincent, P.; SHACHAM, Sharon; MCCAULEY, Dilara; SHECHTER, Sharon
Patent: WO2013/19548 A1, 2013 ;
WO 2013/019548 A1
反应条件
1: tritium; (tricyclohexylphosphine)(1,5-cyclooctadiene)pyridineiridium(I) hexafluorophosphate / dichloromethane / 20 °C 2: methanol / 15 h / 0 °C View Scheme
参考文献
Zhang, Yinsheng; Stolle, Wayne T.
Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 5-6 p. 487 - 489
