2-甲基-3-氧代丁酸叔丁酯合成路线 （共 12 条）
反应条件
CsOH; Br(1-)*C60H44F4N(1+) in diethyl ether
T=-60°C; 72 h; Inert atmosphere; enantioselective reaction;
参考文献
Nagata, Kazuhiro; Sano, Daisuke; Shimizu, Yu; Miyazaki, Michiko; Kanemitsu, Takuya; Itoh, Takashi
Tetrahedron Asymmetry, 2009 , vol. 20, # 21 p. 2530 - 2536
反应条件
1: 1.) sodium ethoxide / 1.) ethanol, 25 deg C, 10 min, 2.) 30 min
2: aq. sodium hydroxide
3: trifluoroacetic acid / 0.5 h
View Scheme
参考文献
Colombo, Lino; Gennari, Cesare; Poli, Giovanni; Scolastico, Carlo; Aragozzini, Fabrizio; Merendi, Cosetta
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 11 p. 2745 - 2749
