1.1: n-butyllithium; TMEDA / tetrahydrofuran / -78 - 20 °C 1.2: 95 percent / tetrahydrofuran / -78 - 20 °C 2.1: silver(II) oxide; nitric acid / dioxane; H2O / 0.03 h / 20 °C 2.2: sodium hydroxide / methanol; H2O / 0.5 h / 20 °C View Scheme

boron tribromide in dichloromethane T=-78 - 20°C; 48 h;