2-甲基-2-丙基[1-羟基-2-(羟基甲基)-2-丁烷基]氨基甲酸酯合成路线 （共 3 条）
反应条件
triethylamine in dichloromethane
T=20°C; 20 h;
参考文献
Honjo, Takashi; Nakao, Michiyasu; Sano, Shigeki; Shiro, Motoo; Yamaguchi, Kentaro; Sei, Yoshihisa; Nagao, Yoshimitsu
Organic Letters, 2007 , vol. 9, # 3 p. 509 - 512
反应条件
1.1: TOYOBO / diisopropyl ether / 4 h / 20 °C
2.1: pyridinium dichromate; molecular sieves 4 Angstroem / CH2Cl2 / 2 h / 20 °C
3.1: potassium tert-butoxide / tetrahydrofuran / 0.25 h / cooling
3.2: tetrahydrofuran / 0.58 h / cooling
4.1: NaOH / methanol; tetrahydrofuran; H2O / 3 h / 20 °C
4.2: potassium tert-butoxide / tetrahydrofuran / 3 h / 20 °C
View Scheme
参考文献
Nakamura, Tsuyoshi; Tsuji, Takashi; Iio, Yukiko; Miyazaki, Shojiro; Takemoto, Toshiyasu; Nishi, Takahide
Tetrahedron Asymmetry, 2006 , vol. 17, # 19 p. 2781 - 2792
反应条件
1.1: TOYOBO / diisopropyl ether / 4 h / 20 °C
2.1: pyridinium dichromate; molecular sieves 4 Angstroem / CH2Cl2 / 2 h / 20 °C
3.1: potassium tert-butoxide / tetrahydrofuran / 0.25 h / cooling
3.2: tetrahydrofuran / 0.58 h / cooling
4.1: NaOH / methanol; tetrahydrofuran; H2O / 3 h / 20 °C
4.2: potassium tert-butoxide / tetrahydrofuran / 3 h / 20 °C
View Scheme
参考文献
Nakamura, Tsuyoshi; Tsuji, Takashi; Iio, Yukiko; Miyazaki, Shojiro; Takemoto, Toshiyasu; Nishi, Takahide
Tetrahedron Asymmetry, 2006 , vol. 17, # 19 p. 2781 - 2792
