(7E,9E)-beta-离子亚基乙醛合成路线 （共 19 条）
反应条件
1: 85 percent / potassium hydroxide / methanol / 64 h / 20 °C 2: 49.8 percent / copper acetate / pyridine; various solvent(s) / 2 h / 100 °C / other solvents, other temperatures, other times View Scheme
参考文献
Valla, Alain; Le Guillou, Regis; Cartier, Dominique; Labia, Roger
Tetrahedron Letters, 2003 , vol. 44, # 25 p. 4737 - 4740
参考文献
Matsui et al.
Journal of Vitaminology, 1958 , vol. 4, p. 190,192
反应条件
1: 72 percent / 1N-NaOH 2: 17 percent / 1.) LDA, 2.) (COOH)2 / 1.) THF, -78 deg C View Scheme
参考文献
Akita, Hiroyuki
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1796 - 1799
反应条件
1: 75 percent / tBuOK / methanol / 48 h / 20 °C 2: piperidine; pyridine / Heating View Scheme
参考文献
Valla, Alain; Valla, Benoist; Le Guillou, Regis; Cartier, Dominique; Dufosse, Laurent; Labia, Roger
Helvetica Chimica Acta, 2007 , vol. 90, # 3 p. 512 - 520
反应条件
1: lithium diisopropyl amide / tetrahydrofuran / -78 °C 2: copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); isopropylamine / 3.5 h 3: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C 4: zinc / water; isopropyl alcohol / 26 h / 40 °C View Scheme
参考文献
McLean, Neville J.; Gansmuller, Axel; Concistre, Maria; Brown, Lynda J.; Levitt, Malcom H.; Brown, Richard C.D.
Tetrahedron, 2011 , vol. 67, # 43 p. 8404 - 8410
反应条件
1: 85 percent / LDA / tetrahydrofuran / -78 °C 2: 79 percent / Pd(PPH3)4; CuI; i-PrNH2 / 20 °C 3: 89 percent / TBAF / tetrahydrofuran / 20 °C View Scheme
参考文献
McLean, Neville J.; Gansmuller, Axel; Concistre, Maria; Brown, Lynda J.; Levitt, Malcom H.; Brown, Richard C.D.
Tetrahedron, 2011 , vol. 67, # 43 p. 8404 - 8410
反应条件
1: 75 percent / tBuOK / methanol / 48 h / 20 °C 2: piperidine; pyridine / Heating View Scheme
参考文献
Valla, Alain; Valla, Benoist; Le Guillou, Regis; Cartier, Dominique; Dufosse, Laurent; Labia, Roger
Helvetica Chimica Acta, 2007 , vol. 90, # 3 p. 512 - 520
反应条件
1: MeOK 2: KOH / methanol; H2O 3: Ba(OH)2 / benzene / 0.5 h View Scheme
参考文献
Wada; Fukunaga; Ito
Synlett, 2001 , # 6 p. 800 - 802
参考文献
Matsui et al.
Journal of Vitaminology, 1958 , vol. 4, p. 190,192
反应条件
1: 20 °C 2: DIBAL-H View Scheme
参考文献
Uenishi, Jun'ichi; Kawahama, Reiko; Yonemitsu, Osamu; Wada, Akimori; Ito, Masayoshi
Angewandte Chemie - International Edition, 1998 , vol. 37, # 3 p. 320 - 323
