1: 3-(2-methyl-[1,3]dioxolan-2-yl)-1-bromobenzene With magnesium in tetrahydrofuran Heating; 2: ethyl-α,α,α-trifluoroacetate T=-78°C; 3: With hydrogenchloride T=20°C;

1: 3-(2-methyl-[1,3]dioxolan-2-yl)-1-bromobenzene; cyclopropyl-magnesium bromide With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran 5 h; Heating / reflux; 2: cyclopropyl-magnesium bromide in tetrahydrofuran 5 h; Heating / reflux; 3: With hydrogenchloride in tetrahydrofuran; water T=20°C; 1.5 h;

1: 1.) Mg, I2 / 1.) anhydrous THF, 4 h, 60 deg C, 2.) THF 2: 97 percent / H2O, 10percent HCl / methanol / 1 h / Ambient temperature 3: 1.) t-BuOK / 1.) anhydrous THF, 30 min, RT, 2.) THF, RT, 24 h 4: 58 percent / LAH / diethyl ether / 6 h / -78 °C 5: 93 percent / m-CPBA (80 percent) / CH2Cl2 / 0.67 h / 0 °C 6: 97 percent / H2, 1M NaOH / 10percent Pd/C / ethanol / 6 h / -60 °C 7: 98 percent / ICl / CH2Cl2 / Ambient temperature 8: RuCl3*H2O, NaIO4 / CCl4; acetonitrile; H2O / Ambient temperature 9: 1.) ZnCl2, 2.) dichlorobis(triphenylphosphine)palladium(II), DIBALH / 1.) ether, THF, RT, 10 min, 2.) ether, THF, RT, 1.5 h View Scheme