4-氯-N-(4-氯苯基)苯甲酰胺合成路线 （共 22 条）
反应条件
potassium tert-butylate in tetrahydrofuran 24 h; Ambient temperature;
参考文献
Ono; Aoki; Tamura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 5 p. 1379 - 1388
反应条件
1: 1.) LDA / 1.) THF, hexane, 0 deg C, 2.) room temperature 2: 1 N sodium ethoxide / ethanol; tetrahydrofuran / Ambient temperature View Scheme
参考文献
Ono; Araya; Todoriki; Tamura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 7 p. 1824 - 1831
反应条件
1: 1.) LDA / 1.) THF, hexane, 0 deg C, 2.) room temperature 2: 1 N sodium ethoxide / ethanol; tetrahydrofuran / Ambient temperature 3: water, AcOH / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Ono; Araya; Todoriki; Tamura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 7 p. 1824 - 1831
反应条件
tert.-butylnitrite; palladium diacetate; acetic acid; tris-(o-tolyl)phosphine in N,N-dimethyl-formamide
T=50°C; P=7500.75 Torr; 16 h; Autoclave;
参考文献
Wu, Xiao-Feng; Schranck, Johannes; Neumann, Helfried; Beller, Matthias
Tetrahedron Letters, 2011 , vol. 52, # 29 p. 3702 - 3704
反应条件
FeCl3-montmorillonite in toluene
0.133333 h; Heating;
参考文献
Pai; Bajpai; Deshpande; Samant
Synthetic Communications, 1997 , vol. 27, # 3 p. 379 - 384
反应条件
triethylamine in ethyl acetate
T=20°C;
参考文献
Van Den Nieuwendijk, Adrianus M. C. H.; Pietra, Daniele; Heitman, Laura; Goeblyoes, Aniko; IJzerman, Adriaan P.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 3 p. 663 - 672
反应条件
copper(l) iodide; manganese(II) fluoride; rel-(R,R)-DACH; potassium hydroxide in water
T=60°C; 24 h;
参考文献
Teo, Yong-Chua; Yong, Fui-Fong; Ithnin, Idzham Khalid; Yio, Siew-Hui Trionna; Lin, Zhiyin
European Journal of Organic Chemistry, 2013 , # 3 p. 515 - 524
反应条件
boron trifluoride diethyl etherate; 3-chloro-benzenecarboperoxoic acid in water
T=0°C; 6 h;
参考文献
An, Gwang-Il; Kim, Misoo; Kim, Jin Yeon; Rhee, Hakjune
Tetrahedron Letters, 2003 , vol. 44, # 10 p. 2183 - 2186
反应条件
1: 100 percent / hydroxylamine hydrochloride; sodium acetate trihydrate / aq. methanol / Heating
2: 89 percent / mercury(II) chloride / acetonitrile / 8 h / 80 °C
View Scheme
参考文献
Ramalingan, Chennan; Park, Yong-Tae
Journal of Organic Chemistry, 2007 , vol. 72, # 12 p. 4536 - 4538
反应条件
silver hexafluoroantimonate; antimony(V) pentachloride in 1,2-dichloro-ethane
3 h; Heating;
参考文献
Harada; Ohno; Kobayashi; Mukaiyama
Synthesis, 1991 , # 12 p. 1216 - 1220
