2-氯-3,4-二氨基吡啶合成路线 (共 20 条)
反应条件
1: T=20°C; 12 h; 2: With hydrogenchloride; water
参考文献
Dainippon Sumitomo Pharma Co., Ltd.
Patent: EP1690863 A1, 2006 ;
Location in patent: Page/Page column 120-121 ;
参考文献
Bremer
Justus Liebigs Annalen der Chemie, 1935 , vol. 518, p. 274,287
Full Text Show Details
Talik; Plazek
Roczniki Chemii, 1956 , vol. 30, p. 1139,1144
Chem.Abstr., 1957 , p. 12089
反应条件
in pyridine 6 h; Heating;
参考文献
Yutilov, Yu.M.; Svertilova, I.A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1988 , p. 653 - 658
Khimiya Geterotsiklicheskikh Soedinenii, 1988 , vol. 24, # 6 p. 799 - 804
参考文献
Middleton; Wibberley
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 8 p. 1757 - 1760
反应条件
1: in nitrobenzene
T=175°C; 0.5 h; Microwave irradiation;
2: With Montmorillonite K 10 clay in nitrobenzene
T=175°C; 0.5 h; Microwave irradiation;
参考文献
MERCK and CO., INC.
Patent: WO2006/23750 A2, 2006 ;
Location in patent: Page/Page column 62 ;
WO 2006/023750 A2
参考文献
Middleton; Wibberley
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 8 p. 1757 - 1760
参考文献
Middleton; Wibberley
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 8 p. 1757 - 1760
参考文献
Middleton; Wibberley
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 8 p. 1757 - 1760
参考文献
Middleton; Wibberley
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 8 p. 1757 - 1760
参考文献
MERCK and CO., INC.
Patent: WO2006/23750 A2, 2006 ;
Location in patent: Page/Page column 61 ;
WO 2006/023750 A2