3,5-二三氟甲基苯磺酰氯合成路线 （共 5 条）
反应条件
hydrogenchloride; sulfur dioxide; copper dichloride; sodium nitrite 1.) AcOH, 0 deg C; Yield given. Multistep reaction;
参考文献
Hoffman, Robert V.; Belfoure, Edward L.
Journal of the American Chemical Society, 1982 , vol. 104, # 8 p. 2183 - 2189
反应条件
n-butyllithium 1.) THF, hexane, -70 deg C, 45 min, 2.) THF, hexane, -70 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Toja, E; Gorini, C; Zirotti, C; Barzaghi, F; Galliani, G
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 4 p. 403 - 413
反应条件
potassium formiate T=200°C; 7 h; neat (no solvent);
参考文献
Zhou, Shaodong; Qian, Chao; Chen, Xinzhi
Synthetic Communications, 2012 , vol. 42, # 16 p. 2432 - 2439
反应条件
ammonia; triethylamine in water; N,N-dimethyl-formamide
T=20°C; 16 h;
参考文献
Kinsella, Michael; Duggan, Patrick G.; Muldoon, Jimmy; Eccles, Kevin S.; Lawrence, Simon E.; Lennon, Claire M.
European Journal of Organic Chemistry, 2011 , # 6 p. 1125 - 1132
反应条件
ammonia in carbon dioxide; water; acetic acid
参考文献
Merck and Co., Inc.
Patent: US3987199 A1, 1976 ;
