2-氯-10-(3-二甲基氨基丙基)吩噻嗪-1-醇合成路线 （共 7 条）
反应条件
1: With ethylenediaminetetraacetic acid trisodium salt; oxygen; Mn(CH3COO)2*4H2O; ascorbic acid powder in water
Udenfriend reaction; pH=4;
2: With iron sulphate heptahydrate; ethylenediaminetetraacetic acid trisodium salt; oxygen in water
T=45°C; Udenfriend reaction; 2 h;
参考文献
Slavik, Roger; Peters, Jens-Uwe; Giger, Rudolf; Buerkler, Markus; Bald, Eric
Tetrahedron Letters, 2011 , vol. 52, # 7 p. 749 - 752
反应条件
1: (i) SO3, H2SO4, (ii) HNO3
2: K2CO3 / acetone
3: (i) NaOiPr, (ii) /BRN= 2562110/
4: H2 / Pt
5: K2CO3, I2 / Cu / dimethylformamide / Heating
6: (i) NaH, xylene, (ii) aq. HCl
View Scheme
参考文献
Grotta,H.M. et al.
Journal of Heterocyclic Chemistry, 1967 , vol. 4, p. 611 - 618
反应条件
1: K2CO3 / acetone
2: (i) NaOiPr, (ii) /BRN= 2562110/
3: H2 / Pt
4: K2CO3, I2 / Cu / dimethylformamide / Heating
5: (i) NaH, xylene, (ii) aq. HCl
View Scheme
参考文献
Grotta,H.M. et al.
Journal of Heterocyclic Chemistry, 1967 , vol. 4, p. 611 - 618
反应条件
1: H2 / Pt
2: K2CO3, I2 / Cu / dimethylformamide / Heating
3: (i) NaH, xylene, (ii) aq. HCl
View Scheme
参考文献
Grotta,H.M. et al.
Journal of Heterocyclic Chemistry, 1967 , vol. 4, p. 611 - 618
反应条件
1: (i) NaOiPr, (ii) /BRN= 2562110/
2: H2 / Pt
3: K2CO3, I2 / Cu / dimethylformamide / Heating
4: (i) NaH, xylene, (ii) aq. HCl
View Scheme
参考文献
Grotta,H.M. et al.
Journal of Heterocyclic Chemistry, 1967 , vol. 4, p. 611 - 618
反应条件
1: K2CO3, I2 / Cu / dimethylformamide / Heating
2: (i) NaH, xylene, (ii) aq. HCl
View Scheme
参考文献
Grotta,H.M. et al.
Journal of Heterocyclic Chemistry, 1967 , vol. 4, p. 611 - 618
反应条件
(i) NaH, xylene, (ii) aq. HCl; Multistep reaction;
参考文献
Grotta,H.M. et al.
Journal of Heterocyclic Chemistry, 1967 , vol. 4, p. 611 - 618
