2-(4-溴苯)乙胺盐酸盐合成路线 (共 3 条)
反应条件
1: With titanium(IV) isopropylate; 1,1,3,3-tetramethyldisiloxane in toluene T=60°C; 24 h; Inert atmosphere; 2: With hydrogenchloride in water T=20°C;
参考文献
Laval, Stephane; Dayoub, Wissam; Favre-Reguillon, Alain; Berthod, Mikael; Demonchaux, Patrice; Mignani, Gerard; Lemaire, Marc
Tetrahedron Letters, 2009 , vol. 50, # 50 p. 7005 - 7007
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 2 h; 2: With hydrogenchloride in ethyl acetate
参考文献
Chytil, Milan; Engel, Sharon R.; Fang, Qun Kevin; Spear, Kerry L.
Patent: US2010/204214 A1, 2010 ;
Location in patent: Page/Page column 112 ;
反应条件
hydrogenchloride in water 0.5 h; Reflux;
参考文献
Runyon, Scott P.; Mosier, Philip D.; Roth, Bryan L.; Glennon, Richard A.; Westkaemper, Richard B.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 21 p. 6808 - 6828