3-三氟甲基-4-溴苯胺合成路线 （共 30 条）
反应条件
C6mim(1+)Br(1-); copper(ll) bromide 1 h; regioselective reaction;
参考文献
Wang, Han; Wen, Kun; Nurahmat, Nurbiya; Shao, Yan; Zhang, He; Wei, Chao; Li, Ya; Shen, Yongjia; Sun, Zhihua
Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 744 - 748
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
McBee et al.
Journal of the American Chemical Society, 1951 , vol. 73, p. 3932
反应条件
1: sulfuric acid; fuming nitric acid 2: SnCl2; aq.-ethanolic HCl View Scheme
参考文献
McBee et al.
Journal of the American Chemical Society, 1951 , vol. 73, p. 3932
反应条件
bromine; acetic acid
参考文献
Tarrant; Lilyquist
Journal of the American Chemical Society, 1953 , vol. 75, p. 3034
反应条件
N-bromosuccinmide in 1,4-dioxane T=20°C;
参考文献
Bartoli, Sandra; Cipollone, Amalia; Squarcia, Antonella; Madami, Andrea; Fattori, Daniela
Synthesis, 2009 , # 8 art. no. P12608SS, p. 1305 - 1308
反应条件
N-bromosuccinmide in dimethyl sulfoxide T=20°C;
参考文献
Bartoli, Sandra; Cipollone, Amalia; Squarcia, Antonella; Madami, Andrea; Fattori, Daniela
Synthesis, 2009 , # 8 art. no. P12608SS, p. 1305 - 1308
反应条件
magnesium sulfate in water; sodium nitrite
参考文献
American Cyanamid Company
Patent: US5707995 A1, 1998 ;
反应条件
sulfuric acid; sodium nitrite anschliessendes Erwaermen mit wss. H2SO4 unter Einleiten von Wasserdampf;
参考文献
McBee; Rapkin
Journal of the American Chemical Society, 1951 , vol. 73, p. 1325
反应条件
hydrogenchloride; sodium nitrite anschliessend Erwaermen mit Kupfer-Pulver;
参考文献
Tarrant; Lilyquist
Journal of the American Chemical Society, 1953 , vol. 75, p. 3034
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2008/56150 A1, 2008 ;
Location in patent: Page/Page column 187 ;
WO 2008/056150 A1
