4-氯-3,5-二硝基三氟甲苯合成路线 （共 44 条）
反应条件
dibromo-difluoro-methane; copper in N,N-dimethyl acetamide T=100°C; 0.5 h;
参考文献
Clark, James H.; McClinton, Martin A.; Blade, Robert J.
Journal of the Chemical Society, Chemical Communications, 1988 , # 10 p. 638 - 639
反应条件
triethylamine in ethanol 1 h; Heating;
参考文献
Benbow, John W.; Bernberg, Erin L.; Korda, Anna; Mead, Jan R.
Antimicrobial Agents and Chemotherapy, 1998 , vol. 42, # 2 p. 339 - 343
参考文献
Reese, Colin B.; Pei-Zhuo, Zhang
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 19 p. 2291 - 2302
反应条件
oxygen; triethylamine in N,N-dimethyl-formamide 1.5 h; Ambient temperature;
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 54, # 1/4 p. 87 - 93
参考文献
Finchimica S.p.A.
Patent: US5405999 A1, 1995 ;
反应条件
1: 53 percent / NEt3 / ethanol / 1) 60 deg C, 3h, 2) r.t. 3h 2: 3 percent / 1) (NH4)2S, 2) acetone / 1) dioxane-water, 70 deg C, 5min, r.t., 8h; 2) 70 deg C, 20 min View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 48, # 1-4 p. 173 - 180
反应条件
1: 69 percent / NaI, glacial acetic acid / acetone / 24 h / 63 - 65 °C 2: 77 percent / KF, o-phthaloyl dichloride / tetrahydrothiophene 1,1-dioxide / 24 h / 180 - 200 °C 3: 40 percent / KNO2 / dimethylformamide / 20 h / 130 - 140 °C View Scheme
参考文献
Khalfina; Rogozhnikova; Vlasov
Russian Journal of Organic Chemistry, 1996 , vol. 32, # 9 p. 1325 - 1331
反应条件
potassium fluoride; 3,4,5,6-tetrafluorophthaloyldifluoride in sulfolane T=150°C; 1.5 h;
参考文献
Journal of Organic Chemistry, , vol. 56, # 22 p. 6406 - 6411
参考文献
Malichenko,B.F. et al.
Sov. Prog. Chem. (Engl. Transl.), 1967 , vol. 33, # 12 p. 1273 - 1275,39 - 41
参考文献
Hoechst Aktiengesellschaft
Patent: US4338473 A1, 1982 ;
