1,1,9-三氯-1-壬烯合成路线 （共 4 条）
反应条件
1: n-PrLi / diethyl ether; tetrahydrofuran; benzene / -20 -> 20 deg C, 1.5 h 2: 1.) HMPA, 2.) KI / 1.) ether, THF, benzene, 20 deg C, 12 h, 2.) glacial acetic acid, reflux, 20 h 3: 7 g / hydrogen / Lindlar catalyst / hexane / 15 °C View Scheme
参考文献
Zakharkin, L. I.; Zhigareva, G. G.; Petrushkina, E. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 9 p. 1750 - 1752
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , vol. 30, # 9 p. 2131 - 2132
反应条件
1: aqueous 2-methoxy-ethanol / 120 °C 2: lithium alanate; diethyl ether 3: aqueous H2SO4 View Scheme
参考文献
Nesmejanow et al.
Zhurnal Obshchei Khimii, 1957 , vol. 27, p. 2418,2422;engl.Ausg.S.2481,2484
反应条件
1: n-PrLi / diethyl ether; tetrahydrofuran; benzene / -20 -> 20 deg C, 1.5 h
2: HMPA / diethyl ether; tetrahydrofuran; benzene / 12 h / 20 °C
View Scheme
参考文献
Zakharkin, L. I.; Zhigareva, G. G.; Petrushkina, E. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 9 p. 1750 - 1752
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , vol. 30, # 9 p. 2131 - 2132
反应条件
1: n-PrLi / diethyl ether; tetrahydrofuran; benzene / -20 -> 20 deg C, 1.5 h
2: 1.) HMPA / 1.) ether, THF, benzene, 20 deg C, 12 h, 2.) DMSO, 100-110 deg C, 5 h
3: 6 g / hydrogen / Lindlar catalyst / hexane / 20 °C
4: 91 percent / (i-Bu)2AlH / diethyl ether / 1 h / 20 °C
View Scheme
参考文献
Zakharkin, L. I.; Zhigareva, G. G.; Petrushkina, E. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 9 p. 1750 - 1752
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , vol. 30, # 9 p. 2131 - 2132
