3,4-二羟基-5-甲氧基苯甲酸甲酯合成路线 （共 32 条）
反应条件
manganese(IV) oxide; water 0.0833333 h; Title compound not separated from byproducts.;
参考文献
Kindler, Bernhard L. J.; Spiteller, Peter
Angewandte Chemie - International Edition, 2007 , vol. 46, # 42 p. 8076 - 8078
参考文献
Matsumoto; Imai; Yamaguchi; et al.
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 1 p. 346 - 351
反应条件
1: 98 percent / CsF / dimethylformamide / 2 h / Heating 2: 98 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 0.5 h 3: 91 percent / PCC, NaOAc / CH2Cl2 / 2 h 4: 1) n-BuLi / 1) THF, -50 deg C to RT, 20 min, 2) THF, RT, 30 min View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 65, # 10 p. 2390 - 2396
反应条件
potassium hydroxide in ethanol T=50°C; 3 h;
参考文献
Saito, Shizuka; Kawabata, Jun
Helvetica Chimica Acta, 2006 , vol. 89, # 7 p. 1395 - 1407
反应条件
1: 98 percent / 1,3-dibromo-5,5-dimethylhydantoin / CHCl3 / 24 h / 20 °C 2: 84 percent / potassium fluoride / dimethylformamide / 110 °C View Scheme
参考文献
Tetrahedron, , vol. 61, # 7 p. 1909 - 1918
反应条件
1: 98 percent / 1,3-dibromo-5,5-dimethylhydantoin / CHCl3 / 24 h / 20 °C 2: 84 percent / potassium fluoride / dimethylformamide / 110 °C 3: 85 percent / copper / dimethylformamide / 16 h / 180 °C View Scheme
参考文献
Chang, Junbiao; Chen, Rongfeng; Guo, Ruiyun; Dong, Chunhong; Zhao, Kang
Helvetica Chimica Acta, 2003 , vol. 86, # 6 p. 2239 - 2246
参考文献
Benard, Christophe; Zouhiri, Fatima; Normand-Bayle, Marie; Danet, Michele; Desmaele, Didier; Leh, Herve; Mouscadet, Jean-Francois; Mbemba, Gladys; Thomas, Claire-Marie; Bonnenfant, Sabine; Le Bret, Marc; D'Angelo, Jean
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 10 p. 2473 - 2476
反应条件
1: 49.7 g / KF / dimethylformamide / 2.5 h / Heating 2: 41.0 g / LiALH4 / tetrahydrofuran / 2 h / Heating 3: 26.0 g / Pyridinium dichlorochromate / CH2Cl2 / 2 h / Ambient temperature View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 58, # 1 p. 346 - 351
反应条件
cesium fluoride in N,N-dimethyl-formamide 2 h; Heating;
参考文献
ARIZONA BOARD OF REGENTS
Patent: EP276051 B1, 1991 ;
反应条件
caesium carbonate in N,N-dimethyl-formamide T=120°C;
参考文献
Takaoka, Shigeki; Takaoka, Noriko; Minoshima, Yuka; Huang, Jian-Mei; Kubo, Miwa; Harada, Kenichi; Hioki, Hideaki; Fukuyama, Yoshiyasu
Tetrahedron, 2009 , vol. 65, # 40 p. 8354 - 8361
