3,4-二羟基-5-甲氧基苯甲酸甲酯合成路线 （共 32 条）
反应条件
1.1: K2CO3 / acetone
2.1: 77 percent / HNO3 / 2 h / 0 - 5 °C
3.1: 34 percent / SnCl2*2H2O; aq. HCl / 0.5 h / Heating
4.1: NaNO2; aq. HBr / 0 - 5 °C
4.2: 69 percent / CuBr; aq. HBr
View Scheme
参考文献
Chang, Junbiao; Chen, Rongfeng; Guo, Ruiyun; Dong, Chunhong; Zhao, Kang
Helvetica Chimica Acta, 2003 , vol. 86, # 6 p. 2239 - 2246
反应条件
1.1: K2CO3 / acetone
2.1: 77 percent / HNO3 / 2 h / 0 - 5 °C
3.1: 34 percent / SnCl2*2H2O; aq. HCl / 0.5 h / Heating
4.1: NaNO2; aq. HBr / 0 - 5 °C
4.2: 69 percent / CuBr; aq. HBr
5.1: 81 percent / aq. KOH / 5 h / Heating
View Scheme
参考文献
Chang, Junbiao; Guo, Xiaohe; Cheng, Senxiang; Guo, Ruiyun; Chen, Rongfeng; Zhao, Kang
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2131 - 2136
