反应条件
1.1: Rh[5(S)-MEPY]4 / CH2Cl2 / Heating
2.1: 93 percent / AlMe3 / CH2Cl2; hexane / 72 h
3.1: 97 percent / 2,6-lutidine / CH2Cl2 / 0.5 h / 0 °C
4.1: 92 percent / NaHMDS / tetrahydrofuran / 1.5 h / 0 °C
5.1: 86 percent / BH3*NH3; LDA / tetrahydrofuran / 1.5 h / 0 °C
6.1: 99 percent / Ph3P; DEAD / tetrahydrofuran / 18 h / 20 °C
7.1: 82 percent / MCPBA; NaHCO3 / CH2Cl2 / 24 h / 20 °C
8.1: NaHMDS / dimethylformamide / -60 - 20 °C
8.2: 14 percent / TFA / tetrahydrofuran; H2O / 3 h / 20 °C
9.1: 92 percent / Dess-Martin periodinane / CH2Cl2 / 1.5 h / 20 °C
10.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C
10.2: 31 mg / tetrahydrofuran; hexane / 2 h / -78 °C
11.1: Na2HPO4; sodium amalgam / methanol / 3 h / -30 °C
11.2: 9 mg / HF*pyridine / tetrahydrofuran / 16 h / 20 °C
12.1: 95 percent / aq. LiOH / tetrahydrofuran / 3.5 h / 20 °C
View Scheme
参考文献
Berberich, Stephen M.; Cherney, Robert J.; Colucci, John; Courillon, Christine; Geraci, Leo S.; Kirkland, Thomas A.; Marx, Matthew A.; Schneider, Matthias F.; Martin, Stephen F.
Tetrahedron, 2003 , vol. 59, # 35 p. 6819 - 6832
