Moore, Michael J. B.; Schultes, Christoph M.; Cuesta, Javier; Cuenca, Francisco; Gunaratnam, Mekala; Tanious, Farial A.; Wilson, W. David; Neidle, Stephen
Journal of Medicinal Chemistry, 2006 , vol. 49, # 2 p. 582 - 599
1: 97 percent / 16 h / 50 °C
2: 71 percent / methanol / 0 - 20 °C
3: 69 percent / ammonium formate; Pd/C / dimethylformamide / 16 h / 20 °C
View Scheme
参考文献
Moorhouse, Adam D.; Santos, Ana Mafalda; Gunaratnam, Mekala; Moore, Michael; Neidle, Stephen; Moses, John E.
Journal of the American Chemical Society, 2006 , vol. 128, # 50 p. 15972 - 15973
Moore, Michael J. B.; Schultes, Christoph M.; Cuesta, Javier; Cuenca, Francisco; Gunaratnam, Mekala; Tanious, Farial A.; Wilson, W. David; Neidle, Stephen
Journal of Medicinal Chemistry, 2006 , vol. 49, # 2 p. 582 - 599
1: With hydrogenchloride; tert.-butylnitrite in tetrahydrofuran; water
1.5 h; Cooling with ice;
2: With sodium azide in tetrahydrofuran; water
T=20°C; Cooling with ice;
参考文献
Lombardo, Caterina Maria; Martinez, Iria Sanchez; Haider, Shozeb; Gabelica, Valerie; De Pauw, Edwin; Moses, John E.; Neidle, Stephen
Chemical Communications, 2010 , vol. 46, # 48 p. 9116 - 9118
